Simplified ultrasound screening for fetal brain function based on behavioral pattern

Seiichi Morokuma, Kotaro Fukushima, Yasuo Yumoto, Mio Uchimura, Arisa Fujiwara, Megumi Matsumoto, Shoji Satoh, Hitoo Nakano

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Despite the longstanding conclusion that behavior can reveal aspects of underlying anatomy and function, no generalized antenatal behavior screening has been developed to identify fetuses that may have central nervous system defects requiring further evaluation. We devised a brief ultrasound examination to distinguish fetuses with compromised central nervous system function from the general population and evaluated it with this study. The study design compared behavioral findings obtained by retrospectively reviewing the ultrasound examinations of 5 fetuses that had abnormal behavior with prospectively obtained findings of 29 normal fetuses. Median time for brief examination criteria was 50 min (range, 30-60 min). The only case undetectable by this brief ultrasound examination has an eye-movement period significantly longer than the normal upper limit. Using this method as a screening test may make it possible to include assessment of fetal brain function as part of routine antenatal care.

Original languageEnglish
Pages (from-to)177-181
Number of pages5
JournalEarly Human Development
Volume83
Issue number3
DOIs
Publication statusPublished - Mar 1 2007

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Fetus
Brain
Central Nervous System
Prenatal Care
Eye Movements
Prenatal Diagnosis
Anatomy
Population

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

Morokuma, S., Fukushima, K., Yumoto, Y., Uchimura, M., Fujiwara, A., Matsumoto, M., ... Nakano, H. (2007). Simplified ultrasound screening for fetal brain function based on behavioral pattern. Early Human Development, 83(3), 177-181. https://doi.org/10.1016/j.earlhumdev.2006.05.012

Simplified ultrasound screening for fetal brain function based on behavioral pattern. / Morokuma, Seiichi; Fukushima, Kotaro; Yumoto, Yasuo; Uchimura, Mio; Fujiwara, Arisa; Matsumoto, Megumi; Satoh, Shoji; Nakano, Hitoo.

In: Early Human Development, Vol. 83, No. 3, 01.03.2007, p. 177-181.

Research output: Contribution to journalArticle

Morokuma, S, Fukushima, K, Yumoto, Y, Uchimura, M, Fujiwara, A, Matsumoto, M, Satoh, S & Nakano, H 2007, 'Simplified ultrasound screening for fetal brain function based on behavioral pattern', Early Human Development, vol. 83, no. 3, pp. 177-181. https://doi.org/10.1016/j.earlhumdev.2006.05.012
Morokuma, Seiichi ; Fukushima, Kotaro ; Yumoto, Yasuo ; Uchimura, Mio ; Fujiwara, Arisa ; Matsumoto, Megumi ; Satoh, Shoji ; Nakano, Hitoo. / Simplified ultrasound screening for fetal brain function based on behavioral pattern. In: Early Human Development. 2007 ; Vol. 83, No. 3. pp. 177-181.
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