Simulation study on the effect of fiber loss to the compound action potential of a sural nerve

Takehito Hayami, Keiji Iramina, Xian Chen, Kenji Sunagawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper reports the result of computer simulation about compound action potential of a sural nerve with and without fiber loss. A compound action potential is a wave of electric potential detectable on the skin after electric stimulation of a peripheral nerve. The loss of nerve fibers, which is observed in some neuropathies, is considered as the cause of low amplitude and slow conduction of the wave. To quantify the relationship between fiber loss and compound action potential, computer simulation of the stimulation of a human sural nerve was executed. As a result, the conduction velocity of the first negative peak of the compound action potential was substantially reduced in case of thick fiber loss, and was slightly enlarged in case of thin fiber loss. However the amplitude of the peak was not always reduced. The effect of thin fiber loss was observed in the amplitude of the second positive peak and the second negative peak.

Original languageEnglish
Title of host publication29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Pages2396-2399
Number of pages4
DOIs
Publication statusPublished - Dec 1 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

Fingerprint

Sural Nerve
Action Potentials
Fibers
Computer Simulation
Peripheral Nerves
Nerve Fibers
Electric Stimulation
Computer simulation
Skin
Electric potential

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Hayami, T., Iramina, K., Chen, X., & Sunagawa, K. (2007). Simulation study on the effect of fiber loss to the compound action potential of a sural nerve. In 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 (pp. 2396-2399). [4352810] https://doi.org/10.1109/IEMBS.2007.4352810

Simulation study on the effect of fiber loss to the compound action potential of a sural nerve. / Hayami, Takehito; Iramina, Keiji; Chen, Xian; Sunagawa, Kenji.

29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07. 2007. p. 2396-2399 4352810.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hayami, T, Iramina, K, Chen, X & Sunagawa, K 2007, Simulation study on the effect of fiber loss to the compound action potential of a sural nerve. in 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07., 4352810, pp. 2396-2399, 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, France, 8/23/07. https://doi.org/10.1109/IEMBS.2007.4352810
Hayami T, Iramina K, Chen X, Sunagawa K. Simulation study on the effect of fiber loss to the compound action potential of a sural nerve. In 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07. 2007. p. 2396-2399. 4352810 https://doi.org/10.1109/IEMBS.2007.4352810
Hayami, Takehito ; Iramina, Keiji ; Chen, Xian ; Sunagawa, Kenji. / Simulation study on the effect of fiber loss to the compound action potential of a sural nerve. 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07. 2007. pp. 2396-2399
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