Single-base mutation assay by capillary electrophoresis using polyacrylamide-DNA block copolymers as affinity ligands

Naoki Kanayama, Hideaki Shibata, Tohru Takarada, Mizuo Maeda

Research output: Contribution to conferencePaper

Abstract

Affinity capillary electrophoresis was developed for single-base mutation discrimination by using a DNA-polyacrylamide (PAAm) block copolymer as a pseudo-immobilized affinity ligand with the fine chemical structure and the narrow molecular weight distribution. The effect of molecular weight of PAAm segment on single-base mutation discrimination was systematically examined.

Original languageEnglish
Number of pages1
Publication statusPublished - Dec 1 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period9/20/069/22/06

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All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Kanayama, N., Shibata, H., Takarada, T., & Maeda, M. (2006). Single-base mutation assay by capillary electrophoresis using polyacrylamide-DNA block copolymers as affinity ligands. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.