Single channel recordings of calcium currents in chick cochlear hair cells

T. Kimitsuki, T. Nakagawa, K. Hisashi, S. Komune, S. Komiyama

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Single Ca2+ channel currents were recorded from chick cochlear hair cells by using cell-attached patches. The elementary current was about - 2 pA at 70 mV positive to the resting potential (R.P.+ 70 mV); the slope conductance over a 40 mV voltage range was 24 pS. The open time histogram was reasonably well expressed by a single exponential function, while the closed time histogram was expressed by a sum of two exponential functions. The Ca2+ channel was activated around R.P.+ 60 mV and the average ensemble current did not decay during 130 ms depolarization, suggesting that the Ca2+ channel in chick cochlear hair cells is the L-type. The Ca2+ channel has three modes of gating behavior, expressed as current records with brief openings (mode 1), no openings (mode 0), or long-lasting openings and very brief closings (mode 2).

Original languageEnglish
Pages (from-to)144-148
Number of pages5
JournalActa Oto-Laryngologica
Volume114
Issue number2
DOIs
Publication statusPublished - Jan 1 1994

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Auditory Hair Cells
Calcium Channels
Membrane Potentials

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Single channel recordings of calcium currents in chick cochlear hair cells. / Kimitsuki, T.; Nakagawa, T.; Hisashi, K.; Komune, S.; Komiyama, S.

In: Acta Oto-Laryngologica, Vol. 114, No. 2, 01.01.1994, p. 144-148.

Research output: Contribution to journalArticle

Kimitsuki, T. ; Nakagawa, T. ; Hisashi, K. ; Komune, S. ; Komiyama, S. / Single channel recordings of calcium currents in chick cochlear hair cells. In: Acta Oto-Laryngologica. 1994 ; Vol. 114, No. 2. pp. 144-148.
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