Single neuron activity of rat hypothalamic paraventricular nucleus during body suspension

Toshihiko Katafuchi, Yutaka Oomura, Kazuhiko Aoyagi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Single neuron activity in the hypothalamic paraventricular nucleus (PVN) was recorded during horizontal and 45° head-down tilt suspension in unanesthetized rats. When the rats were raised in the head-down position, 13 of 34 neurons (38%) in the PVN changed activity as follows: gradual decrease ( 11 13, type I), or gradual increase ( 2 13, type II). Responses of 6 type I and 1 type II neuron were smaller during horizontal suspension. Intracerebroventricular or intraperitoneal injection of hypertonic saline caused an increase in activity of 4 of 5 type I neurons tested. This hyperosmotic stimulation had no effect during suppressed activity induced by head-down tilt. These results suggest that the activity of PVN neurons is altered during body suspension, probably by information from baroreceptors in the thoracic activity, proprioreceptors and/or the vestibular organ, and these neurons might be involved in regulation of the autonomic and neuroendocrine systems.

Original languageEnglish
Pages (from-to)301-306
Number of pages6
JournalNeuroscience Letters
Volume78
Issue number3
DOIs
Publication statusPublished - Aug 5 1987

Fingerprint

Paraventricular Hypothalamic Nucleus
Suspensions
Neurons
Head-Down Tilt
Neurosecretory Systems
Pressoreceptors
Intraperitoneal Injections
Thorax
Head

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Single neuron activity of rat hypothalamic paraventricular nucleus during body suspension. / Katafuchi, Toshihiko; Oomura, Yutaka; Aoyagi, Kazuhiko.

In: Neuroscience Letters, Vol. 78, No. 3, 05.08.1987, p. 301-306.

Research output: Contribution to journalArticle

Katafuchi, Toshihiko ; Oomura, Yutaka ; Aoyagi, Kazuhiko. / Single neuron activity of rat hypothalamic paraventricular nucleus during body suspension. In: Neuroscience Letters. 1987 ; Vol. 78, No. 3. pp. 301-306.
@article{b97df628da0342f89ceeab1535f6c096,
title = "Single neuron activity of rat hypothalamic paraventricular nucleus during body suspension",
abstract = "Single neuron activity in the hypothalamic paraventricular nucleus (PVN) was recorded during horizontal and 45° head-down tilt suspension in unanesthetized rats. When the rats were raised in the head-down position, 13 of 34 neurons (38{\%}) in the PVN changed activity as follows: gradual decrease ( 11 13, type I), or gradual increase ( 2 13, type II). Responses of 6 type I and 1 type II neuron were smaller during horizontal suspension. Intracerebroventricular or intraperitoneal injection of hypertonic saline caused an increase in activity of 4 of 5 type I neurons tested. This hyperosmotic stimulation had no effect during suppressed activity induced by head-down tilt. These results suggest that the activity of PVN neurons is altered during body suspension, probably by information from baroreceptors in the thoracic activity, proprioreceptors and/or the vestibular organ, and these neurons might be involved in regulation of the autonomic and neuroendocrine systems.",
author = "Toshihiko Katafuchi and Yutaka Oomura and Kazuhiko Aoyagi",
year = "1987",
month = "8",
day = "5",
doi = "10.1016/0304-3940(87)90377-6",
language = "English",
volume = "78",
pages = "301--306",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Single neuron activity of rat hypothalamic paraventricular nucleus during body suspension

AU - Katafuchi, Toshihiko

AU - Oomura, Yutaka

AU - Aoyagi, Kazuhiko

PY - 1987/8/5

Y1 - 1987/8/5

N2 - Single neuron activity in the hypothalamic paraventricular nucleus (PVN) was recorded during horizontal and 45° head-down tilt suspension in unanesthetized rats. When the rats were raised in the head-down position, 13 of 34 neurons (38%) in the PVN changed activity as follows: gradual decrease ( 11 13, type I), or gradual increase ( 2 13, type II). Responses of 6 type I and 1 type II neuron were smaller during horizontal suspension. Intracerebroventricular or intraperitoneal injection of hypertonic saline caused an increase in activity of 4 of 5 type I neurons tested. This hyperosmotic stimulation had no effect during suppressed activity induced by head-down tilt. These results suggest that the activity of PVN neurons is altered during body suspension, probably by information from baroreceptors in the thoracic activity, proprioreceptors and/or the vestibular organ, and these neurons might be involved in regulation of the autonomic and neuroendocrine systems.

AB - Single neuron activity in the hypothalamic paraventricular nucleus (PVN) was recorded during horizontal and 45° head-down tilt suspension in unanesthetized rats. When the rats were raised in the head-down position, 13 of 34 neurons (38%) in the PVN changed activity as follows: gradual decrease ( 11 13, type I), or gradual increase ( 2 13, type II). Responses of 6 type I and 1 type II neuron were smaller during horizontal suspension. Intracerebroventricular or intraperitoneal injection of hypertonic saline caused an increase in activity of 4 of 5 type I neurons tested. This hyperosmotic stimulation had no effect during suppressed activity induced by head-down tilt. These results suggest that the activity of PVN neurons is altered during body suspension, probably by information from baroreceptors in the thoracic activity, proprioreceptors and/or the vestibular organ, and these neurons might be involved in regulation of the autonomic and neuroendocrine systems.

UR - http://www.scopus.com/inward/record.url?scp=0023225520&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023225520&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(87)90377-6

DO - 10.1016/0304-3940(87)90377-6

M3 - Article

C2 - 3627567

AN - SCOPUS:0023225520

VL - 78

SP - 301

EP - 306

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 3

ER -