TY - JOUR
T1 - Single-slice epicardial fat area measurement
T2 - Do we need to measure the total epicardial fat volume?
AU - Oyama, Noriko
AU - Goto, Daisuke
AU - Ito, Yoichi M.
AU - Ishimori, Naoki
AU - Mimura, Rie
AU - Furumoto, Tomoo
AU - Kato, Fumi
AU - Tsutsui, Hiroyuki
AU - Tamaki, Nagara
AU - Terae, Satoshi
AU - Shirato, Hiroki
N1 - Funding Information:
Acknowledgment. This research was partially funded by a Grant-in-Aid for Young Scientists (B) from the Ministry of Education, Science, Sports, and Culture of Japan.
PY - 2011/2
Y1 - 2011/2
N2 - Purpose: The aim of this study was to assess a method for measuring epicardial fat volume (EFV) by means of a single-slice area measurement. We investigated the relation between a single-slice fat area measurement and total EFV. Methods and methods: A series of 72 consecutive patients (ages 65 ± 11 years; 36 men) who had undergone cardiac computed tomography (CT) on a 64-slice multidetector scanner with prospective electrocardiographic triggering were retrospectively reviewed. Pixels in the pericardium with a density range from -230 to -30 Hounsfield units were considered fat, giving the per-slice epicardial fat area (EFA). The EFV was estimated by the summation of EFAs multiplied by the slice thickness. We investigated the relation between total EFV and each EFA. Results: EFAs measured at several anatomical landmarks-right pulmonary artery, origins of the left main coronary artery, right coronary artery, coronary sinus-all correlated with the EFV (r = 0.77-0.92). The EFA at the LMCA level was highly reproducible and showed an excellent correlation with the EFV (r = 0.92). Conclusion: The EFA is significantly correlated with the EFV. The EFA is a simple, quick method for representing the time-consuming EFV, which has been used as a predictive indicator of cardiovascular diseases.
AB - Purpose: The aim of this study was to assess a method for measuring epicardial fat volume (EFV) by means of a single-slice area measurement. We investigated the relation between a single-slice fat area measurement and total EFV. Methods and methods: A series of 72 consecutive patients (ages 65 ± 11 years; 36 men) who had undergone cardiac computed tomography (CT) on a 64-slice multidetector scanner with prospective electrocardiographic triggering were retrospectively reviewed. Pixels in the pericardium with a density range from -230 to -30 Hounsfield units were considered fat, giving the per-slice epicardial fat area (EFA). The EFV was estimated by the summation of EFAs multiplied by the slice thickness. We investigated the relation between total EFV and each EFA. Results: EFAs measured at several anatomical landmarks-right pulmonary artery, origins of the left main coronary artery, right coronary artery, coronary sinus-all correlated with the EFV (r = 0.77-0.92). The EFA at the LMCA level was highly reproducible and showed an excellent correlation with the EFV (r = 0.92). Conclusion: The EFA is significantly correlated with the EFV. The EFA is a simple, quick method for representing the time-consuming EFV, which has been used as a predictive indicator of cardiovascular diseases.
UR - http://www.scopus.com/inward/record.url?scp=79952471992&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952471992&partnerID=8YFLogxK
U2 - 10.1007/s11604-010-0524-z
DO - 10.1007/s11604-010-0524-z
M3 - Article
C2 - 21359935
AN - SCOPUS:79952471992
SN - 1867-1071
VL - 29
SP - 104
EP - 109
JO - Japanese Journal of Radiology
JF - Japanese Journal of Radiology
IS - 2
ER -
