Six cases of orbital apex syndrome

Yoko Fujita, Hiroshi Yoshikawa, Toshio Hisatomi, Hiromasa Takenouchi, Kumiko Hirayama, Muneki Miura, Takako Ito, Sei Ichi Ishimoto, Yoh Ichi Kawano, Tatsuro Ishibashi

Research output: Contribution to journalArticlepeer-review


We observed 6 cases of orbital apex syndrome during the foregoing 10 years. All the cases showed visual loss, periorbital or hemicranial pain, and restricted ocular movement in all directions. All the cases were males. Their ages ranged from 46 to 77 years, average 59 years. The underlying causes included mycosis 2 cases, metastatic tumor 1 case, hypertrophic pachymeningitis 1 case and unkown 2 cases. The main lesion was located in the cavernous sinus 2 cases, superior orbital fissure 2 cases, dura mater 1 case, and unidentified 1 case. Five cases lost vision in the affected side. Three cases resulted in death. We advocate early diagnosis and treatment of orbital apex syndrome which may result in visual loss or fatal outcome.

Original languageEnglish
Pages (from-to)975-981
Number of pages7
JournalJapanese Journal of Clinical Ophthalmology
Issue number6
Publication statusPublished - Jun 1 2005

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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