Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues

Yasutaka Anraku, Akihiro Kishimura, Atsushi Kobayashi, Makoto Oba, Kazunori Kataoka

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Selective disposition of nanocarriers into target tissue is an essential issue in drug delivery. Critical size of nanocarriers (∼150 nm) discriminating the permeability into normal and tumor tissues was determined by the use of size-tunable, polyion complex hollow vesicles (PICsome) as a ruler.

Original languageEnglish
Pages (from-to)6054-6056
Number of pages3
JournalChemical Communications
Volume47
Issue number21
DOIs
Publication statusPublished - Jun 7 2011
Externally publishedYes

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Tumors
Tissue
Drug delivery

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues. / Anraku, Yasutaka; Kishimura, Akihiro; Kobayashi, Atsushi; Oba, Makoto; Kataoka, Kazunori.

In: Chemical Communications, Vol. 47, No. 21, 07.06.2011, p. 6054-6056.

Research output: Contribution to journalArticle

Anraku, Yasutaka ; Kishimura, Akihiro ; Kobayashi, Atsushi ; Oba, Makoto ; Kataoka, Kazunori. / Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues. In: Chemical Communications. 2011 ; Vol. 47, No. 21. pp. 6054-6056.
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