Slender stalk with combined features of saccular limited dorsal myeloschisis and congenital dermal sinus in a neonate

Yoshitaka Tomita, Takato Morioka, Nobuya Murakami, Yushi Noguchi, Yuka Sato, Satoshi Suzuki

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Limited dorsal myeloschisis (LDM) and congenital dermal sinus (CDS) originate from incomplete disjunction between the cutaneous and neural ectoderms. Some LDM stalks have been found to have elements of a CDS or dermoid cyst. We surgically treated a saccular lesion in the lumbosacral region of a 7-day-old male neonate. Although fetal magnetic resonance imaging (MRI) failed to reveal a stalk, postnatal MRI including three-dimensional heavily T2-weighted imaging demonstrated a stalk originating from the lumbar cord and extending caudally to enter the lumbosacral meningocele sac. During untethering surgery, we found that the stalk was slender, with a diameter of 0.7-0.8 mm, but otherwise appeared to be a typical LDM stalk. Histopathological examination revealed that the fibrocollagenous stalk contained glial fibrillary acidic protein-immunopositive neuroglial tissues and stratified squamous epithelium. The present report describes the first documented case of a stalk with combined features of saccular LDM and CDS in a neonate. Since cutaneous ectodermal tissue is likely to remain in the remnant stalk, this patient requires careful monitoring to detect the potential development of a dermoid cyst.

Original languageEnglish
Pages (from-to)125-131
Number of pages7
JournalPediatric Neurosurgery
Volume54
Issue number2
DOIs
Publication statusPublished - Mar 1 2019

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Spina Bifida Occulta
Dermoid Cyst
Newborn Infant
Magnetic Resonance Imaging
Meningocele
Lumbosacral Region
Skin
Ectoderm
Glial Fibrillary Acidic Protein
Spinal Cord
Epithelium

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Clinical Neurology

Cite this

Slender stalk with combined features of saccular limited dorsal myeloschisis and congenital dermal sinus in a neonate. / Tomita, Yoshitaka; Morioka, Takato; Murakami, Nobuya; Noguchi, Yushi; Sato, Yuka; Suzuki, Satoshi.

In: Pediatric Neurosurgery, Vol. 54, No. 2, 01.03.2019, p. 125-131.

Research output: Contribution to journalArticle

Tomita, Yoshitaka ; Morioka, Takato ; Murakami, Nobuya ; Noguchi, Yushi ; Sato, Yuka ; Suzuki, Satoshi. / Slender stalk with combined features of saccular limited dorsal myeloschisis and congenital dermal sinus in a neonate. In: Pediatric Neurosurgery. 2019 ; Vol. 54, No. 2. pp. 125-131.
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