TY - JOUR
T1 - Small hepatocellular carcinoma on magnetic resonance imaging
T2 - Relation of signal intensity to angiographic and clinicopathologic findings
AU - Honda, Hiroshi
AU - Kaneko, Kuniyuki
AU - Maeda, Takashi
AU - Kuroiwa, Toshirou
AU - Fukuya, Tatsurou
AU - Yoshimitsu, Kengo
AU - Irie, Hiroyuki
AU - Aibe, Hitoshi
AU - Takenaka, Kenji
AU - Masuda, Kouji
PY - 1997/3/8
Y1 - 1997/3/8
N2 - RATIONALE AND OBJECTIVES. The authors discuss the clinicopathologic features and angiographic vascularity of various signal intensity patterns on magnetic resonance (MR) imaging of small hepatocellular carcinomas (HCCs). METHODS. Magnetic resonance images of 88 resected HCCs (≤3 cm) were obtained using T1- and T2-weighted spin-echo images and T1-weighted images after gadolinium (Gd)-DTPA administration. Images were compared with angiographic and histopathologic findings. RESULTS. Forty HCCs (45%) were depicted on T1- weighted images, 51 (58%) on T2-weighted images, and 41 (49%) on T1-weighted images after Gd-DTPA administration. Overall, 64 (76%) were found on at least one image. On T1-weighted images, hyperintense HCCs histologically showed fatty metamorphosis and portal tracts within the tumor. On T2-weighted images, HCC hyperintensity correlated with expansive growth, peliotic change, and hypervascularity. By contrast, HCCs that were undetected or hypointense on T2-weighted images were well differentiated with replacing growth and portal tracts. On T1-weighted images after Gd-DTPA, hyperintense HCCs had peliotic change; undetected HCCs were well differentiated and hypovascular. CONCLUSIONS. Histologic grade, vascularity, portal tracts and peliotic change correlate with MR signal intensity. For hyperintense HCCs on T1-weighted images and hypo- or isointense HCCs on T2-weighted images, treatment methods must be assigned with the consideration that HCCs may be receiving transsinusoidal and portal blood supplies.
AB - RATIONALE AND OBJECTIVES. The authors discuss the clinicopathologic features and angiographic vascularity of various signal intensity patterns on magnetic resonance (MR) imaging of small hepatocellular carcinomas (HCCs). METHODS. Magnetic resonance images of 88 resected HCCs (≤3 cm) were obtained using T1- and T2-weighted spin-echo images and T1-weighted images after gadolinium (Gd)-DTPA administration. Images were compared with angiographic and histopathologic findings. RESULTS. Forty HCCs (45%) were depicted on T1- weighted images, 51 (58%) on T2-weighted images, and 41 (49%) on T1-weighted images after Gd-DTPA administration. Overall, 64 (76%) were found on at least one image. On T1-weighted images, hyperintense HCCs histologically showed fatty metamorphosis and portal tracts within the tumor. On T2-weighted images, HCC hyperintensity correlated with expansive growth, peliotic change, and hypervascularity. By contrast, HCCs that were undetected or hypointense on T2-weighted images were well differentiated with replacing growth and portal tracts. On T1-weighted images after Gd-DTPA, hyperintense HCCs had peliotic change; undetected HCCs were well differentiated and hypovascular. CONCLUSIONS. Histologic grade, vascularity, portal tracts and peliotic change correlate with MR signal intensity. For hyperintense HCCs on T1-weighted images and hypo- or isointense HCCs on T2-weighted images, treatment methods must be assigned with the consideration that HCCs may be receiving transsinusoidal and portal blood supplies.
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U2 - 10.1097/00004424-199703000-00005
DO - 10.1097/00004424-199703000-00005
M3 - Article
C2 - 9055129
AN - SCOPUS:0031056892
VL - 32
SP - 161
EP - 168
JO - Investigative Radiology
JF - Investigative Radiology
SN - 0020-9996
IS - 3
ER -