Abstract
The progress of nanotechnology has opened the path for the development of new biomaterials. Recent developments have demonstrated that sol-gel bioceramics play an important role in the biomedical field due to their superior biological and mechanical properties. A bioactive hydroxyapatite (HA) is a common bioceramic that attaches to living tissues in vivo at body temperature. Sol-gel processes are now being used to produce bioactive coatings, powders, and substrates that can facilitate control over biological behavior of proteins and cells with broad clinical applications. It has been found that HA particles can down-regulate the expression of some cancerogenic genes in 432tumor cells. The nano-HA particles from the biodegradation of HA ceramics could penetrate the membranes of tumor cells. A rapid and economic sol-gel method has been designed to synthesize sodium silicate (Na 2 SiO 3 ) into silica gel in large quantities. Sol-gel-based bioceramics have the potential to present unexpected excellent biological functions. Thus, the understanding and control of the interactions between bioceramics and biological entities may play one of the leading roles in the development of nanomedicine.
| Original language | English |
|---|---|
| Title of host publication | Smart Ceramics |
| Subtitle of host publication | Preparation, Properties, and Applications |
| Publisher | Pan Stanford Publishing Pte. Ltd. |
| Pages | 431-442 |
| Number of pages | 12 |
| ISBN (Electronic) | 9781351671644 |
| ISBN (Print) | 9789814774307 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Engineering(all)
- Materials Science(all)
Cite this
Sol-gel-based bioceramics : From materials to medicine. / Arora, Bharti; Park, Ji Hoon; Choi, Eun Ha; Attri, Pankaj.
Smart Ceramics: Preparation, Properties, and Applications. Pan Stanford Publishing Pte. Ltd., 2018. p. 431-442.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Sol-gel-based bioceramics
T2 - From materials to medicine
AU - Arora, Bharti
AU - Park, Ji Hoon
AU - Choi, Eun Ha
AU - Attri, Pankaj
PY - 2018/1/1
Y1 - 2018/1/1
N2 - The progress of nanotechnology has opened the path for the development of new biomaterials. Recent developments have demonstrated that sol-gel bioceramics play an important role in the biomedical field due to their superior biological and mechanical properties. A bioactive hydroxyapatite (HA) is a common bioceramic that attaches to living tissues in vivo at body temperature. Sol-gel processes are now being used to produce bioactive coatings, powders, and substrates that can facilitate control over biological behavior of proteins and cells with broad clinical applications. It has been found that HA particles can down-regulate the expression of some cancerogenic genes in 432tumor cells. The nano-HA particles from the biodegradation of HA ceramics could penetrate the membranes of tumor cells. A rapid and economic sol-gel method has been designed to synthesize sodium silicate (Na 2 SiO 3 ) into silica gel in large quantities. Sol-gel-based bioceramics have the potential to present unexpected excellent biological functions. Thus, the understanding and control of the interactions between bioceramics and biological entities may play one of the leading roles in the development of nanomedicine.
AB - The progress of nanotechnology has opened the path for the development of new biomaterials. Recent developments have demonstrated that sol-gel bioceramics play an important role in the biomedical field due to their superior biological and mechanical properties. A bioactive hydroxyapatite (HA) is a common bioceramic that attaches to living tissues in vivo at body temperature. Sol-gel processes are now being used to produce bioactive coatings, powders, and substrates that can facilitate control over biological behavior of proteins and cells with broad clinical applications. It has been found that HA particles can down-regulate the expression of some cancerogenic genes in 432tumor cells. The nano-HA particles from the biodegradation of HA ceramics could penetrate the membranes of tumor cells. A rapid and economic sol-gel method has been designed to synthesize sodium silicate (Na 2 SiO 3 ) into silica gel in large quantities. Sol-gel-based bioceramics have the potential to present unexpected excellent biological functions. Thus, the understanding and control of the interactions between bioceramics and biological entities may play one of the leading roles in the development of nanomedicine.
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U2 - 10.1201/9781315163598
DO - 10.1201/9781315163598
M3 - Chapter
AN - SCOPUS:85052476639
SN - 9789814774307
SP - 431
EP - 442
BT - Smart Ceramics
PB - Pan Stanford Publishing Pte. Ltd.
ER -