Sol-gel synthesis and in vitro cell compatibility analysis of silicate-containing biodegradable hybrid gels

Kanji Tsuru; Z. Robertson; B. Annaz; I. R. Gibson; S. M. Best; Y. Shirosaki; S. Hayakawa; A. Osaka

Sol-gel synthesis and in vitro cell compatibility analysis of silicate-containing biodegradable hybrid gels

Kanji Tsuru, Z. Robertson, B. Annaz, I. R. Gibson, S. M. Best, Y. Shirosaki, S. Hayakawa, A. Osaka

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7 Citations (Scopus)

Abstract

Novel hybrid gels in the system gelatin-GPTMS-TEOS were prepared via a sol-gel route, and their ability to release Si(TV) was examined using MG63 osteoblast-like cell culture. The amount of Si released and the release rate were controllable by changing the mixing ratio of GPTMS and TEOS. In addition, the hybrids had biocompatible surfaces. It is expected that the hybrids will be utilized for the investigation of the effect of Si on cell differentiation and tissue regeneration.

Original language	English
Pages (from-to)	447-450
Number of pages	4
Journal	Key Engineering Materials
Volume	361-363 I
Publication status	Published - Jan 22 2008

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

Cite this

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abstract = "Novel hybrid gels in the system gelatin-GPTMS-TEOS were prepared via a sol-gel route, and their ability to release Si(TV) was examined using MG63 osteoblast-like cell culture. The amount of Si released and the release rate were controllable by changing the mixing ratio of GPTMS and TEOS. In addition, the hybrids had biocompatible surfaces. It is expected that the hybrids will be utilized for the investigation of the effect of Si on cell differentiation and tissue regeneration.",

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T1 - Sol-gel synthesis and in vitro cell compatibility analysis of silicate-containing biodegradable hybrid gels

AU - Tsuru, Kanji

AU - Robertson, Z.

AU - Annaz, B.

AU - Gibson, I. R.

AU - Best, S. M.

AU - Shirosaki, Y.

AU - Hayakawa, S.

AU - Osaka, A.

PY - 2008/1/22

Y1 - 2008/1/22

N2 - Novel hybrid gels in the system gelatin-GPTMS-TEOS were prepared via a sol-gel route, and their ability to release Si(TV) was examined using MG63 osteoblast-like cell culture. The amount of Si released and the release rate were controllable by changing the mixing ratio of GPTMS and TEOS. In addition, the hybrids had biocompatible surfaces. It is expected that the hybrids will be utilized for the investigation of the effect of Si on cell differentiation and tissue regeneration.

AB - Novel hybrid gels in the system gelatin-GPTMS-TEOS were prepared via a sol-gel route, and their ability to release Si(TV) was examined using MG63 osteoblast-like cell culture. The amount of Si released and the release rate were controllable by changing the mixing ratio of GPTMS and TEOS. In addition, the hybrids had biocompatible surfaces. It is expected that the hybrids will be utilized for the investigation of the effect of Si on cell differentiation and tissue regeneration.

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M3 - Article

AN - SCOPUS:38148998817

SN - 1013-9826

VL - 361-363 I

SP - 447

EP - 450

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Sol-gel synthesis and in vitro cell compatibility analysis of silicate-containing biodegradable hybrid gels

Abstract

All Science Journal Classification (ASJC) codes

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