Solid pancreatic hamartoma

Shigenori Nagata, Koji Yamaguchi, Takahiro Inoue, Hiroshi Yamaguchi, Tetsuhide Ito, Junya Gibo, Masao Tanaka, Masazumi Tsuneyoshi

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A case of solid pancreatic hamartoma in a 58-year-old Japanese woman is presented. She had no symptoms, and a pancreatic mass was incidentally found on screening ultrasonography 4 months before admission. The patient was not alcoholic and had no history of pancreatitis. Physical examination and laboratory data were unremarkable. Preoperative imaging demonstrated a nodule in the body of the pancreas, measuring 2.0 cm in maximum diameter, which showed marked delayed enhancement during dynamic CT. The patient underwent a distal pancreatectomy under the preoperative diagnosis of pancreatic endocrine tumor and had an uneventful postoperative course. A well-demarcated solid nodule, 1.9 cm in diameter, was evident in the body of the pancreas. Microscopically, the lesion was composed of non-neoplastic, disarranged acinar cells and ducts embedded in a sclerotic stroma with elongated spindle cells, lacking discrete islets. The stromal spindle cells were immunoreactive for CD34 and CD117. The histological diagnosis was solid hamartoma of the pancreas. There was no recurrence 5 months after surgery. Herein is reported a case of solid hamartoma of the pancreas and review of the literature. A search through the literature found only two cases of solid hamartoma of the pancreas, among the 14 cases previously reported as pancreatic hamartoma.

Original languageEnglish
Pages (from-to)276-280
Number of pages5
JournalPathology International
Volume57
Issue number5
DOIs
Publication statusPublished - May 1 2007

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Hamartoma
Pancreas
Pancreatectomy
Acinar Cells
Stromal Cells
Pancreatitis
Physical Examination
Ultrasonography
Recurrence
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Nagata, S., Yamaguchi, K., Inoue, T., Yamaguchi, H., Ito, T., Gibo, J., ... Tsuneyoshi, M. (2007). Solid pancreatic hamartoma. Pathology International, 57(5), 276-280. https://doi.org/10.1111/j.1440-1827.2007.02090.x

Solid pancreatic hamartoma. / Nagata, Shigenori; Yamaguchi, Koji; Inoue, Takahiro; Yamaguchi, Hiroshi; Ito, Tetsuhide; Gibo, Junya; Tanaka, Masao; Tsuneyoshi, Masazumi.

In: Pathology International, Vol. 57, No. 5, 01.05.2007, p. 276-280.

Research output: Contribution to journalArticle

Nagata, S, Yamaguchi, K, Inoue, T, Yamaguchi, H, Ito, T, Gibo, J, Tanaka, M & Tsuneyoshi, M 2007, 'Solid pancreatic hamartoma', Pathology International, vol. 57, no. 5, pp. 276-280. https://doi.org/10.1111/j.1440-1827.2007.02090.x
Nagata S, Yamaguchi K, Inoue T, Yamaguchi H, Ito T, Gibo J et al. Solid pancreatic hamartoma. Pathology International. 2007 May 1;57(5):276-280. https://doi.org/10.1111/j.1440-1827.2007.02090.x
Nagata, Shigenori ; Yamaguchi, Koji ; Inoue, Takahiro ; Yamaguchi, Hiroshi ; Ito, Tetsuhide ; Gibo, Junya ; Tanaka, Masao ; Tsuneyoshi, Masazumi. / Solid pancreatic hamartoma. In: Pathology International. 2007 ; Vol. 57, No. 5. pp. 276-280.
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