Solid-solid synthesis of a hydrophobic vitamin B12 having a benzo-18-crown-6 moiety at the C10 position of the corrin ring

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    Abstract

    A new hydrophobic vitamin B12 having a benzo-18-crown-6 moiety at the C-10 position of the corrin ring was synthesized by solid-state condensation reaction. The proton NMR titration study in acetonitrile exhibits a potassium ion binding behavior of the hydrophobic vitamin B12 at the benzo-18-crown-6 moiety.

    Original languageEnglish
    Pages (from-to)6421-6424
    Number of pages4
    JournalTetrahedron Letters
    Volume44
    Issue number34
    DOIs
    Publication statusPublished - Aug 18 2003

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry

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