A new hydrophobic vitamin B12 having a benzo-18-crown-6 moiety at the C-10 position of the corrin ring was synthesized by solid-state condensation reaction. The proton NMR titration study in acetonitrile exhibits a potassium ion binding behavior of the hydrophobic vitamin B12 at the benzo-18-crown-6 moiety.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry