Sonographic diagnostic criteria for screening Sjögren's syndrome

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Abstract

Objective: The objective of this study is to establish readily applied sonographic diagnostic criteria for Sjögren's syndrome. Study design: Sonographic images of 79 cases of previously suspected Sjögren's syndrome (including 43 actual cases) were analyzed retrospectively for the following characteristic features: (1) multiple hypoechoic areas, (2) multiple hyperechoic lines or spots, (3) multiple hypoechoic areas surrounded with hyperechoic lines or spots, and (4) obscuration of the gland configuration. Logistic regression analysis was used to extract valuable sonographic findings. Sonographic images of 80 prospective patients (of whom 48 proved to have Sjögren's syndrome) were scored prospectively using selected features to verify the usefulness of the established criteria. Results: Three sonographic findings in parotid and submandibular glands were selected by logistic regression analysis and retrospective and prospective patients compared. Experienced observers could differentiate positive cases of Sjögren's syndrome from negative controls to a highly significant degree. Findings correlated very well with sialographic grading. Conclusion: Sonography can be substituted for sialography when applying the selected criteria in screening for Sjögren's syndrome.

Original languageEnglish
Pages (from-to)85-93
Number of pages9
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Volume102
Issue number1
DOIs
Publication statusPublished - Jul 1 2006

All Science Journal Classification (ASJC) codes

  • Dentistry(all)
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Surgery

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