SOS-inducible DNA polymerase II of E coli is homologous to replicative DNA polymerase of eukaryotes

H. Shinagawa, H. Iwasaki, Y. Ishino, A. Nakata

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The polB gene of Escherichia coli encodes DNA polymerase II whose role in vivo is not defined. The polB gene has been cloned and shown to be identical to a DNA damage-inducible gene dinA which is regulated by the LexA repressor. Nucleotide sequencing of polB reveals that E coli DNA polymerase II as highly homologous to replicative DNA polymerases of eukaryotes which include human DNA polymerase α and Saccharomyces cerevisiae DNA polymerases I, II and III. The polB gene is not required for growth, UV-repair and UV-mutagenesis.

Original languageEnglish
Pages (from-to)433-435
Number of pages3
JournalBiochimie
Volume73
Issue number4
DOIs
Publication statusPublished - Apr 1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry

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