Specific inhibition of flavin catalyses by a "molecular hinge"

Seiji Shinkai; Gong Xin He; Tsutomu Matsuda; Andrew D. Hamilton; Howard S. Rosenzweig

doi:10.1016/S0040-4039(01)93499-9

Specific inhibition of flavin catalyses by a "molecular hinge"

Seiji Shinkai, Gong Xin He, Tsutomu Matsuda, Andrew D. Hamilton, Howard S. Rosenzweig

Institute for Advanced Study

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

An artificial receptor having both a 2,6-diamidopyridine hydrogen bonding site and a naphthalene stacking site selectively quenched (5-deaza) flavin fluorescence and inhibited flavin-mediated photo-oxidation of 1,4-butanedithiol.

Original language	English
Pages (from-to)	5895-5898
Number of pages	4
Journal	Tetrahedron Letters
Volume	30
Issue number	43
DOIs	https://doi.org/10.1016/S0040-4039(01)93499-9
Publication status	Published - 1989

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)93499-9

Cite this

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title = "Specific inhibition of flavin catalyses by a {"}molecular hinge{"}",

abstract = "An artificial receptor having both a 2,6-diamidopyridine hydrogen bonding site and a naphthalene stacking site selectively quenched (5-deaza) flavin fluorescence and inhibited flavin-mediated photo-oxidation of 1,4-butanedithiol.",

author = "Seiji Shinkai and He, {Gong Xin} and Tsutomu Matsuda and Hamilton, {Andrew D.} and Rosenzweig, {Howard S.}",

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AU - Shinkai, Seiji

AU - He, Gong Xin

AU - Matsuda, Tsutomu

AU - Hamilton, Andrew D.

AU - Rosenzweig, Howard S.

PY - 1989

Y1 - 1989

N2 - An artificial receptor having both a 2,6-diamidopyridine hydrogen bonding site and a naphthalene stacking site selectively quenched (5-deaza) flavin fluorescence and inhibited flavin-mediated photo-oxidation of 1,4-butanedithiol.

AB - An artificial receptor having both a 2,6-diamidopyridine hydrogen bonding site and a naphthalene stacking site selectively quenched (5-deaza) flavin fluorescence and inhibited flavin-mediated photo-oxidation of 1,4-butanedithiol.

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U2 - 10.1016/S0040-4039(01)93499-9

DO - 10.1016/S0040-4039(01)93499-9

M3 - Article

AN - SCOPUS:0001731703

SN - 0040-4039

VL - 30

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EP - 5898

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 43

ER -

Specific inhibition of flavin catalyses by a "molecular hinge"

Abstract

All Science Journal Classification (ASJC) codes

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