Specificity and randomness in the visual cortex

Kenichi Oki, R. Clay Reid

Research output: Contribution to journalReview article

73 Citations (Scopus)

Abstract

Research on the functional anatomy of visual cortical circuits has recently zoomed in from the macroscopic level to the microscopic. High-resolution functional imaging has revealed that the functional architecture of orientation maps in higher mammals is built with single-cell precision. By contrast, orientation selectivity in rodents is dispersed on visual cortex in a salt-and-pepper fashion, despite highly tuned visual responses. Recent studies of synaptic physiology indicate that there are disjoint subnetworks of interconnected cells in the rodent visual cortex. These intermingled subnetworks, described in vitro, may relate to the intermingled ensembles of cells tuned to different orientations, described in vivo. This hypothesis may soon be tested with new anatomic techniques that promise to reveal the detailed wiring diagram of cortical circuits.

Original languageEnglish
Pages (from-to)401-407
Number of pages7
JournalCurrent Opinion in Neurobiology
Volume17
Issue number4
DOIs
Publication statusPublished - Aug 1 2007

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All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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