Spectroscopic characterisation of two polyketide metabolites from Cylindrocarpon sp. from driftwood

Seiya Yoshida, Takuma Suzuki, Hiroshi Furuno, Takako Aboshi, Tetsuya Murayama, Takuya Koseki, Yoshihito Shiono

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Two new polyketides, (5R,7R,9R)-7,9-dihydroxy-5-decanolide and (4E,6R,9R)- 6,9-dihydroxydec-4-enoic acid (2), were isolated from rice cultures of Cylindrocarpon sp. SY-39 discovered during screening of driftwood at a Shonai coast area in Yamagata, Japan. The structures of 1 and 2 were determined using a variety of spectroscopic methods. Compound 2 exhibited moderate antimicrobial activity against Staphylococcus aureus NBRC 13276 and Aspergillus clavatus F 318a at a concentration of 50 μg per disk.

Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalNatural Product Research
Volume32
Issue number1
DOIs
Publication statusPublished - Jan 2 2018

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Aspergillus clavatus
Neonectria
Polyketides
polyketides
Aspergillus
Metabolites
Coastal zones
Staphylococcus aureus
Japan
Screening
anti-infective agents
metabolites
screening
coasts
rice
Acids
acids
methodology
Oryza

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

Cite this

Spectroscopic characterisation of two polyketide metabolites from Cylindrocarpon sp. from driftwood. / Yoshida, Seiya; Suzuki, Takuma; Furuno, Hiroshi; Aboshi, Takako; Murayama, Tetsuya; Koseki, Takuya; Shiono, Yoshihito.

In: Natural Product Research, Vol. 32, No. 1, 02.01.2018, p. 60-64.

Research output: Contribution to journalArticle

Yoshida, Seiya ; Suzuki, Takuma ; Furuno, Hiroshi ; Aboshi, Takako ; Murayama, Tetsuya ; Koseki, Takuya ; Shiono, Yoshihito. / Spectroscopic characterisation of two polyketide metabolites from Cylindrocarpon sp. from driftwood. In: Natural Product Research. 2018 ; Vol. 32, No. 1. pp. 60-64.
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