Spectroscopic characterisation of two polyketide metabolites from Cylindrocarpon sp. from driftwood

Seiya Yoshida, Takuma Suzuki, Hiroshi Furuno, Takako Aboshi, Tetsuya Murayama, Takuya Koseki, Yoshihito Shiono

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Two new polyketides, (5R,7R,9R)-7,9-dihydroxy-5-decanolide and (4E,6R,9R)- 6,9-dihydroxydec-4-enoic acid (2), were isolated from rice cultures of Cylindrocarpon sp. SY-39 discovered during screening of driftwood at a Shonai coast area in Yamagata, Japan. The structures of 1 and 2 were determined using a variety of spectroscopic methods. Compound 2 exhibited moderate antimicrobial activity against Staphylococcus aureus NBRC 13276 and Aspergillus clavatus F 318a at a concentration of 50 μg per disk.

    Original languageEnglish
    Pages (from-to)60-64
    Number of pages5
    JournalNatural Product Research
    Volume32
    Issue number1
    DOIs
    Publication statusPublished - Jan 2 2018

    All Science Journal Classification (ASJC) codes

    • Analytical Chemistry
    • Biochemistry
    • Plant Science
    • Organic Chemistry

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