Abstract
We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.
| Original language | English |
|---|---|
| Pages | 933-936 |
| Number of pages | 4 |
| Publication status | Published - Dec 1 2005 |
| Event | IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005 - Takamatsu, Japan Duration: Dec 6 2005 → Dec 9 2005 |
Other
| Other | IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005 |
|---|---|
| Country | Japan |
| City | Takamatsu |
| Period | 12/6/05 → 12/9/05 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
Spectroscopy-tomography of living single-cells. / Ishimaru, I.; Yasokawa, T.; Yoshida, M.; Ishizaki, K.; Kuriyama, S.; Masaki, T.; Nakai, S.; Takegawa, Kaoru; Tanaka, N.
2005. 933-936 Paper presented at IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005, Takamatsu, Japan.Research output: Contribution to conference › Paper
}
TY - CONF
T1 - Spectroscopy-tomography of living single-cells
AU - Ishimaru, I.
AU - Yasokawa, T.
AU - Yoshida, M.
AU - Ishizaki, K.
AU - Kuriyama, S.
AU - Masaki, T.
AU - Nakai, S.
AU - Takegawa, Kaoru
AU - Tanaka, N.
PY - 2005/12/1
Y1 - 2005/12/1
N2 - We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.
AB - We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.
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M3 - Paper
SP - 933
EP - 936
ER -