Spectroscopy-tomography of living single-cells

I. Ishimaru, T. Yasokawa, M. Yoshida, K. Ishizaki, S. Kuriyama, T. Masaki, S. Nakai, Kaoru Takegawa, N. Tanaka

Research output: Contribution to conferencePaper

Abstract

We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.

Original languageEnglish
Pages933-936
Number of pages4
Publication statusPublished - Dec 1 2005
EventIDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005 - Takamatsu, Japan
Duration: Dec 6 2005Dec 9 2005

Other

OtherIDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005
CountryJapan
CityTakamatsu
Period12/6/0512/9/05

Fingerprint

Microspheres
Spectrometry
Tomography
Spectroscopy
Defects
Interferometry
Phase shift
Liquid crystals
Image processing
Pixels
Color

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Ishimaru, I., Yasokawa, T., Yoshida, M., Ishizaki, K., Kuriyama, S., Masaki, T., ... Tanaka, N. (2005). Spectroscopy-tomography of living single-cells. 933-936. Paper presented at IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005, Takamatsu, Japan.

Spectroscopy-tomography of living single-cells. / Ishimaru, I.; Yasokawa, T.; Yoshida, M.; Ishizaki, K.; Kuriyama, S.; Masaki, T.; Nakai, S.; Takegawa, Kaoru; Tanaka, N.

2005. 933-936 Paper presented at IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005, Takamatsu, Japan.

Research output: Contribution to conferencePaper

Ishimaru, I, Yasokawa, T, Yoshida, M, Ishizaki, K, Kuriyama, S, Masaki, T, Nakai, S, Takegawa, K & Tanaka, N 2005, 'Spectroscopy-tomography of living single-cells' Paper presented at IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005, Takamatsu, Japan, 12/6/05 - 12/9/05, pp. 933-936.
Ishimaru I, Yasokawa T, Yoshida M, Ishizaki K, Kuriyama S, Masaki T et al. Spectroscopy-tomography of living single-cells. 2005. Paper presented at IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005, Takamatsu, Japan.
Ishimaru, I. ; Yasokawa, T. ; Yoshida, M. ; Ishizaki, K. ; Kuriyama, S. ; Masaki, T. ; Nakai, S. ; Takegawa, Kaoru ; Tanaka, N. / Spectroscopy-tomography of living single-cells. Paper presented at IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005, Takamatsu, Japan.4 p.
@conference{a9423a985498442d86b47aba653fa890,
title = "Spectroscopy-tomography of living single-cells",
abstract = "We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.",
author = "I. Ishimaru and T. Yasokawa and M. Yoshida and K. Ishizaki and S. Kuriyama and T. Masaki and S. Nakai and Kaoru Takegawa and N. Tanaka",
year = "2005",
month = "12",
day = "1",
language = "English",
pages = "933--936",
note = "IDW/AD'05 - 12th International Display Workshops in Conjunction with Asia Display 2005 ; Conference date: 06-12-2005 Through 09-12-2005",

}

TY - CONF

T1 - Spectroscopy-tomography of living single-cells

AU - Ishimaru, I.

AU - Yasokawa, T.

AU - Yoshida, M.

AU - Ishizaki, K.

AU - Kuriyama, S.

AU - Masaki, T.

AU - Nakai, S.

AU - Takegawa, Kaoru

AU - Tanaka, N.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.

AB - We propose the spectroscopy-tomography of single cells to improve the early detection and treatment of cancer. This technology can obtain the 3-dimensional distribution of components at a high spatial resolution. In this paper, we mention the analysis result of the cross-sectional images of the microsphere which diameter is 10 μm. The distribution of the internal submicron-defect in the microsphere can be analyzed. And to correct the center of rotation, we propose the image processing that uses the normalized correlation function as estimated value. The cross-sectional image of the microsphere is improved and the vague internal defect becomes to be distinguished by this proposed method. And we mention the proposed variable phase-contrast spectrometry as the 2- dimensional high spatial resolution spectrometry. This proposed method is a phase-shift interferometry between the 0th order diffracted light and the higher order diffracted light. We discuss the experimental results of the spectral characteristics using the proposed variable phase-contrast spectrometry. We measured the spectral characteristics at each pixel using the color filter of the liquid crystal and verified that the 2-dimensional spectral characteristics can be measured with good result.

UR - http://www.scopus.com/inward/record.url?scp=33644585799&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33644585799&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33644585799

SP - 933

EP - 936

ER -