Spin-labeled dendrimers in EPR imaging with low molecular weight nitroxides

Alexander T. Yordanov, Ken-Ichi Yamada, Murali C. Krishna, James B. Mitchell, Eric Woller, Mary Cloninger, Martin W. Brechbiel

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


Sixth-generation PAMAM dendrimers labeled with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO, shown schematically) have been synthesized and are shown to reoxidize EPR-silent hydroxylamines to EPR-active nitroxides. Therefore these dendrimers are potential TEMPO free radical life supporters for EPR imaging.

Original languageEnglish
Pages (from-to)2690-2692
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number14
Publication statusPublished - Jul 16 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)


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