Spiropyran as a regulator of DNA hybridization with reversed switching mode to that of azobenzene

Hiroyuki Asanuma, Kenji Shirasuka, Takayuki Yoshida, Tohru Takarada, Xingguo Liang, Makoto Komiyama

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The nitrospirobenzopyran, tethered at the 5'-end of the homothymidine, was thermally isomerized to colored merocyanine, which was converted reversibly to colorless spiropyran by visible light irradiation (λ > 490 nm). Concurrently with the spiropyran→merocyanine isomerization, melting temperature of the duplex with its complementary oligonucleotide was changed from 18.0 °C to 21.6 °C.

Original languageEnglish
Pages (from-to)108-109
Number of pages2
JournalChemistry Letters
Issue number2
DOIs
Publication statusPublished - Jan 1 2001

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Isomerization
Oligonucleotides
Melting point
Irradiation
DNA
azobenzene
merocyanine
spiropyran

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Spiropyran as a regulator of DNA hybridization with reversed switching mode to that of azobenzene. / Asanuma, Hiroyuki; Shirasuka, Kenji; Yoshida, Takayuki; Takarada, Tohru; Liang, Xingguo; Komiyama, Makoto.

In: Chemistry Letters, No. 2, 01.01.2001, p. 108-109.

Research output: Contribution to journalArticle

Asanuma, Hiroyuki ; Shirasuka, Kenji ; Yoshida, Takayuki ; Takarada, Tohru ; Liang, Xingguo ; Komiyama, Makoto. / Spiropyran as a regulator of DNA hybridization with reversed switching mode to that of azobenzene. In: Chemistry Letters. 2001 ; No. 2. pp. 108-109.
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