A novel aggregation mechanism of DNA-containing colloidal particle based on the stability decrease of colloidal particle accompanied by the duplex formation of the surface DNA with the complementary DNA is proposed. Using the particle aggregation assay according to the present mechanism, the sequence- and the chain length-selective DNA detection is attained.
|Number of pages||5|
|Publication status||Published - 2002|
All Science Journal Classification (ASJC) codes
- Polymers and Plastics
- Materials Chemistry