Stability change of DNA-carrying colloidal particle induced by hybridization with target DNA

Takeshi Mori; Mizuo Maeda

doi:10.1295/polymj.34.624

Stability change of DNA-carrying colloidal particle induced by hybridization with target DNA

Takeshi Mori, Mizuo Maeda

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

A novel aggregation mechanism of DNA-containing colloidal particle based on the stability decrease of colloidal particle accompanied by the duplex formation of the surface DNA with the complementary DNA is proposed. Using the particle aggregation assay according to the present mechanism, the sequence- and the chain length-selective DNA detection is attained.

Original language	English
Pages (from-to)	624-628
Number of pages	5
Journal	Polymer Journal
Volume	34
Issue number	8
DOIs	https://doi.org/10.1295/polymj.34.624
Publication status	Published - 2002

All Science Journal Classification (ASJC) codes

Polymers and Plastics
Materials Chemistry

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10.1295/polymj.34.624

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title = "Stability change of DNA-carrying colloidal particle induced by hybridization with target DNA",

abstract = "A novel aggregation mechanism of DNA-containing colloidal particle based on the stability decrease of colloidal particle accompanied by the duplex formation of the surface DNA with the complementary DNA is proposed. Using the particle aggregation assay according to the present mechanism, the sequence- and the chain length-selective DNA detection is attained.",

author = "Takeshi Mori and Mizuo Maeda",

note = "Funding Information: Acknowledgment. We thank Dr. Tohru Takarada for the valuable discussion and Mr. Zhonglan Tang for the melting temperature measurement. This work was supported in part by a Grant-in-Aid for Scientific Research from Ministry of Education, Culture, Sports, Science and Technology of Japan, and by Research Fellowships of the Japan Society for the Promotion of Science for Young Scientists.",

year = "2002",

doi = "10.1295/polymj.34.624",

language = "English",

volume = "34",

pages = "624--628",

journal = "Polymer Journal",

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T1 - Stability change of DNA-carrying colloidal particle induced by hybridization with target DNA

AU - Mori, Takeshi

AU - Maeda, Mizuo

N1 - Funding Information: Acknowledgment. We thank Dr. Tohru Takarada for the valuable discussion and Mr. Zhonglan Tang for the melting temperature measurement. This work was supported in part by a Grant-in-Aid for Scientific Research from Ministry of Education, Culture, Sports, Science and Technology of Japan, and by Research Fellowships of the Japan Society for the Promotion of Science for Young Scientists.

PY - 2002

Y1 - 2002

N2 - A novel aggregation mechanism of DNA-containing colloidal particle based on the stability decrease of colloidal particle accompanied by the duplex formation of the surface DNA with the complementary DNA is proposed. Using the particle aggregation assay according to the present mechanism, the sequence- and the chain length-selective DNA detection is attained.

AB - A novel aggregation mechanism of DNA-containing colloidal particle based on the stability decrease of colloidal particle accompanied by the duplex formation of the surface DNA with the complementary DNA is proposed. Using the particle aggregation assay according to the present mechanism, the sequence- and the chain length-selective DNA detection is attained.

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DO - 10.1295/polymj.34.624

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EP - 628

JO - Polymer Journal

JF - Polymer Journal

IS - 8

ER -

Stability change of DNA-carrying colloidal particle induced by hybridization with target DNA

Abstract

All Science Journal Classification (ASJC) codes

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