Starvation: An Alternate Measure to Improve Immunity and Physiology of Red Sea Bream During Edwardsiella Tarda Infection.

Sipra Mohapatra, Tapas Chakraborty, Rami Haj-Kacem, Sonoko Shimizu, Takahiro Matsubara, Kohei Ohta

Research output: Contribution to journalArticle

Abstract

Dietary restrictions during infectious challenges are quite common in animal kingdom. In the present investigation, we aimed to explore the positive implications of short-term starvation in Edwardsiella tarda infected red sea breams. Starvation resulted in depleted transcription of several iron binding protein (Hepcidin, Transferrin), which could have reduced the bacterial colonization in starved- infected fish. This was confirmed by the significantly (P<0.05) low bacterial load in the spleen and muscle of starved-infected fish. Gills showed mild damage to the secondary filaments architecture as well as elevated mucus production in the starved-infected fish compared to the fed ones. Massive mucus cell hyperplasia was observed in starved-placebo fish, which further increased after infection. Decreased activities of serum anti-oxidative enzymes and reduced total antioxidant capacity after starvation was suggestive of improved stress response and heightened stress withstanding capacity of these fish. Relatively higher haemoglobin and phagocytic activity along with the increased cytokines (TNFα, IL- 1β) level in starved-infected groups than their fed counterparts indicated the better immune condition of the former group. Additionally, our data also demonstrated that starvation enhanced the survivability and overall disease resistance index of infected fish, indicating that short period of starvation might be a beneficial measure to fight against infections.
Original languageEnglish
Article numberS2
Pages (from-to)007
Number of pages12
JournalJournal of Aquaculture Research & Development
DOIs
Publication statusPublished - Jun 12 2016

Fingerprint

Edwardsiella tarda
Pagrus major
immunity
starvation
physiology
fish
infection
mucus
bacterial colonization
dietary restriction
disease resistance
Red Sea
interleukin-1
transferrin
hemoglobin
phagocytosis
hyperplasia
antioxidant
placebos
sea

Cite this

Starvation: An Alternate Measure to Improve Immunity and Physiology of Red Sea Bream During Edwardsiella Tarda Infection. / Mohapatra, Sipra; Chakraborty, Tapas; Haj-Kacem, Rami; Shimizu, Sonoko; Matsubara, Takahiro; Ohta, Kohei.

In: Journal of Aquaculture Research & Development, 12.06.2016, p. 007.

Research output: Contribution to journalArticle

Mohapatra, Sipra ; Chakraborty, Tapas ; Haj-Kacem, Rami ; Shimizu, Sonoko ; Matsubara, Takahiro ; Ohta, Kohei. / Starvation: An Alternate Measure to Improve Immunity and Physiology of Red Sea Bream During Edwardsiella Tarda Infection. In: Journal of Aquaculture Research & Development. 2016 ; pp. 007.
@article{04c788a200114c20816af23d636e71ff,
title = "Starvation: An Alternate Measure to Improve Immunity and Physiology of Red Sea Bream During Edwardsiella Tarda Infection.",
abstract = "Dietary restrictions during infectious challenges are quite common in animal kingdom. In the present investigation, we aimed to explore the positive implications of short-term starvation in Edwardsiella tarda infected red sea breams. Starvation resulted in depleted transcription of several iron binding protein (Hepcidin, Transferrin), which could have reduced the bacterial colonization in starved- infected fish. This was confirmed by the significantly (P<0.05) low bacterial load in the spleen and muscle of starved-infected fish. Gills showed mild damage to the secondary filaments architecture as well as elevated mucus production in the starved-infected fish compared to the fed ones. Massive mucus cell hyperplasia was observed in starved-placebo fish, which further increased after infection. Decreased activities of serum anti-oxidative enzymes and reduced total antioxidant capacity after starvation was suggestive of improved stress response and heightened stress withstanding capacity of these fish. Relatively higher haemoglobin and phagocytic activity along with the increased cytokines (TNFα, IL- 1β) level in starved-infected groups than their fed counterparts indicated the better immune condition of the former group. Additionally, our data also demonstrated that starvation enhanced the survivability and overall disease resistance index of infected fish, indicating that short period of starvation might be a beneficial measure to fight against infections.",
author = "Sipra Mohapatra and Tapas Chakraborty and Rami Haj-Kacem and Sonoko Shimizu and Takahiro Matsubara and Kohei Ohta",
year = "2016",
month = "6",
day = "12",
doi = "10.4172/2155-9546.S2-007",
language = "English",
pages = "007",
journal = "Journal of Aquaculture Research and Development",
issn = "2155-9546",
publisher = "OMICS Publishing Group",

}

TY - JOUR

T1 - Starvation: An Alternate Measure to Improve Immunity and Physiology of Red Sea Bream During Edwardsiella Tarda Infection.

AU - Mohapatra, Sipra

AU - Chakraborty, Tapas

AU - Haj-Kacem, Rami

AU - Shimizu, Sonoko

AU - Matsubara, Takahiro

AU - Ohta, Kohei

PY - 2016/6/12

Y1 - 2016/6/12

N2 - Dietary restrictions during infectious challenges are quite common in animal kingdom. In the present investigation, we aimed to explore the positive implications of short-term starvation in Edwardsiella tarda infected red sea breams. Starvation resulted in depleted transcription of several iron binding protein (Hepcidin, Transferrin), which could have reduced the bacterial colonization in starved- infected fish. This was confirmed by the significantly (P<0.05) low bacterial load in the spleen and muscle of starved-infected fish. Gills showed mild damage to the secondary filaments architecture as well as elevated mucus production in the starved-infected fish compared to the fed ones. Massive mucus cell hyperplasia was observed in starved-placebo fish, which further increased after infection. Decreased activities of serum anti-oxidative enzymes and reduced total antioxidant capacity after starvation was suggestive of improved stress response and heightened stress withstanding capacity of these fish. Relatively higher haemoglobin and phagocytic activity along with the increased cytokines (TNFα, IL- 1β) level in starved-infected groups than their fed counterparts indicated the better immune condition of the former group. Additionally, our data also demonstrated that starvation enhanced the survivability and overall disease resistance index of infected fish, indicating that short period of starvation might be a beneficial measure to fight against infections.

AB - Dietary restrictions during infectious challenges are quite common in animal kingdom. In the present investigation, we aimed to explore the positive implications of short-term starvation in Edwardsiella tarda infected red sea breams. Starvation resulted in depleted transcription of several iron binding protein (Hepcidin, Transferrin), which could have reduced the bacterial colonization in starved- infected fish. This was confirmed by the significantly (P<0.05) low bacterial load in the spleen and muscle of starved-infected fish. Gills showed mild damage to the secondary filaments architecture as well as elevated mucus production in the starved-infected fish compared to the fed ones. Massive mucus cell hyperplasia was observed in starved-placebo fish, which further increased after infection. Decreased activities of serum anti-oxidative enzymes and reduced total antioxidant capacity after starvation was suggestive of improved stress response and heightened stress withstanding capacity of these fish. Relatively higher haemoglobin and phagocytic activity along with the increased cytokines (TNFα, IL- 1β) level in starved-infected groups than their fed counterparts indicated the better immune condition of the former group. Additionally, our data also demonstrated that starvation enhanced the survivability and overall disease resistance index of infected fish, indicating that short period of starvation might be a beneficial measure to fight against infections.

U2 - 10.4172/2155-9546.S2-007

DO - 10.4172/2155-9546.S2-007

M3 - Article

SP - 007

JO - Journal of Aquaculture Research and Development

JF - Journal of Aquaculture Research and Development

SN - 2155-9546

M1 - S2

ER -