Abstract
Bone morphogenetic proteins (BMP) are cytokines that promote differentiation of mesenchymal stem cells into differentiated osteoblasts and bone formation. Recently, HMG-CoA reductase inhibitors (statins) emerged as a candidate for the treatment of osteoporosis, because they stimulate BMP-2 expression and bone formation. Inhibition of Rho/Rho-kinase pathway may be involved in statin effect on bone formation.
| Original language | English |
|---|---|
| Pages (from-to) | 286-288 |
| Number of pages | 3 |
| Journal | Clinical calcium |
| Volume | 14 |
| Issue number | 2 |
| Publication status | Published - Jan 1 2004 |
All Science Journal Classification (ASJC) codes
- Medicine(all)