Statistical analysis of surgical site infection after head and neck reconstructive surgery

Kenichi Kamizono, Minoru Sakuraba, Shogo Nagamatsu, Shimpei Miyamoto, Ryuichi Hayashi

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Background: Surgical site infections (SSIs) occur at a rate exceeding 40 % after head and neck reconstruction and are due in part to the clean-contaminated surgical field, in which cutaneous fields interact with oral or pharyngeal fields. The aim of this study was to clarify the most important risk factors for SSI and to identify effective strategies for preventing SSI. Methods: In 2011 and 2012, 197 patients who underwent head and neck reconstructive surgery were studied at National Cancer Center Hospital East, Japan. The SSI rate, risk factors for SSI, and biological aspects of SSI were evaluated prospectively. Results: A total of 42 patients (21.3 %) had SSIs, and 62 bacterial species were identified at infection sites. Significant risk factors for SSI identified with multivariate analysis were hypoalbuminemia [P = 0.002, odds ratio (OR) = 3.37], reconstruction with vascularized bone transfer (P = 0.006, OR = 3.99), and a poor American Society of Anesthesiologists Physical Status score (P = 0.041, OR = 3.00). Most bacteria identified were species that persist around cutaneous and pharyngeal fields, but multidrug-resistant bacteria were rare. Conclusions: The SSI rate at our hospital is lower than rates in previous studies. To minimize SSI, intervention to improve the patient's perisurgical nutritional status and a more appropriate mandible reconstructive strategy should be considered.

Original languageEnglish
Pages (from-to)1700-1705
Number of pages6
JournalAnnals of Surgical Oncology
Volume21
Issue number5
DOIs
Publication statusPublished - Jan 1 2014

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Reconstructive Surgical Procedures
Surgical Wound Infection
Neck
Head
Odds Ratio
Bacteria
Cancer Care Facilities
Hypoalbuminemia
Skin
Nutritional Status
Mandible

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology
  • Medicine(all)

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Statistical analysis of surgical site infection after head and neck reconstructive surgery. / Kamizono, Kenichi; Sakuraba, Minoru; Nagamatsu, Shogo; Miyamoto, Shimpei; Hayashi, Ryuichi.

In: Annals of Surgical Oncology, Vol. 21, No. 5, 01.01.2014, p. 1700-1705.

Research output: Contribution to journalArticle

Kamizono, K, Sakuraba, M, Nagamatsu, S, Miyamoto, S & Hayashi, R 2014, 'Statistical analysis of surgical site infection after head and neck reconstructive surgery', Annals of Surgical Oncology, vol. 21, no. 5, pp. 1700-1705. https://doi.org/10.1245/s10434-014-3498-8
Kamizono, Kenichi ; Sakuraba, Minoru ; Nagamatsu, Shogo ; Miyamoto, Shimpei ; Hayashi, Ryuichi. / Statistical analysis of surgical site infection after head and neck reconstructive surgery. In: Annals of Surgical Oncology. 2014 ; Vol. 21, No. 5. pp. 1700-1705.
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