TY - JOUR
T1 - Stereochemical control of calixarenes useful as rigid and conformationally diversiform platforms for molecular design
AU - Otsuka, H.
AU - Shinkai, S.
PY - 1996
Y1 - 1996
N2 - The syntheses of all possible conformational isomers using a protection-deprotection method with a benzyl group and metal template effects are reported. The numbers of chiral isomers are 17 for tetra-O-substituted calix[4]arenes, 9 for tri-O-substituted calix[4]arenes, 3 for di-O-substituted calix[4]arenes, and 0 for mono-O-substituted calix[4]arenes. The synthesis of chiral calix[4]arenes is possible through the introduction of a substituent into the m-position of a phenol unit or by the use of dissymetric `stapling reaction' in proximal phenol units.
AB - The syntheses of all possible conformational isomers using a protection-deprotection method with a benzyl group and metal template effects are reported. The numbers of chiral isomers are 17 for tetra-O-substituted calix[4]arenes, 9 for tri-O-substituted calix[4]arenes, 3 for di-O-substituted calix[4]arenes, and 0 for mono-O-substituted calix[4]arenes. The synthesis of chiral calix[4]arenes is possible through the introduction of a substituent into the m-position of a phenol unit or by the use of dissymetric `stapling reaction' in proximal phenol units.
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U2 - 10.1016/S0968-5677(96)00038-7
DO - 10.1016/S0968-5677(96)00038-7
M3 - Article
AN - SCOPUS:0030392146
VL - 3
SP - 189
EP - 205
JO - Supramolecular Science
JF - Supramolecular Science
SN - 0968-5677
IS - 4
ER -