Stereoselective esterification of dl-menthol by polyurethane-entrapped lipase in organic solvent

Satoru Koshiro, Kenji Sonomoto, Atsuo Tanaka, Saburo Fukui

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Stereospecific esterification of dl-menthol was studied by the use of immobilized lipase in an adequate water-saturated organic solvent system. Lipase from Candida cylindracea immobilized by entrapment with urethane prepolymers and 5-phenylvaleric acid as the acyl donor were chosen based on the stereoselectivity and the yield of l-menthyl ester. Water-saturated cyclohexane or isooctane was found to be the most suitable solvent system. Entrapment significantly enhanced the operational stability of lipase.

Original languageEnglish
Pages (from-to)47-57
Number of pages11
JournalJournal of Biotechnology
Volume2
Issue number1
DOIs
Publication statusPublished - Jan 1 1985
Externally publishedYes

Fingerprint

Menthol
Polyurethanes
Esterification
Lipases
Lipase
Organic solvents
Stereoselectivity
Water
Candida
Urethane
Cyclohexane
Esters
Acids

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Stereoselective esterification of dl-menthol by polyurethane-entrapped lipase in organic solvent. / Koshiro, Satoru; Sonomoto, Kenji; Tanaka, Atsuo; Fukui, Saburo.

In: Journal of Biotechnology, Vol. 2, No. 1, 01.01.1985, p. 47-57.

Research output: Contribution to journalArticle

Koshiro, Satoru ; Sonomoto, Kenji ; Tanaka, Atsuo ; Fukui, Saburo. / Stereoselective esterification of dl-menthol by polyurethane-entrapped lipase in organic solvent. In: Journal of Biotechnology. 1985 ; Vol. 2, No. 1. pp. 47-57.
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