Two chiral intermediates, C(1)-C(9) and C(11)-C(17) portionsof protomycinolide IV, were synthesized both from (S)-ethyl lactatevia asymmetric pinacol-type rearrangement followed bydiastereoselective reactions on α-methyl-β,γ-unsaturatedcarbonyl compounds.
|Number of pages||4|
|Publication status||Published - 1985|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry