Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea

Kuniyoshi Shimizu; Ryuichiro Kondo; Kokki Sakai; Yoshihiro Shoyama; Hiroaki Sato; Tetsuya Ueno

doi:10.1271/bbb.64.875

Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea

Kuniyoshi Shimizu, Ryuichiro Kondo, Kokki Sakai, Yoshihiro Shoyama, Hiroaki Sato, Tetsuya Ueno

Sustainable Bioresources Science

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.

Original language	English
Pages (from-to)	875-877
Number of pages	3
Journal	Bioscience, Biotechnology and Biochemistry
Volume	64
Issue number	4
DOIs	https://doi.org/10.1271/bbb.64.875
Publication status	Published - Jan 1 2000

All Science Journal Classification (ASJC) codes

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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abstract = "The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.",

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AU - Kondo, Ryuichiro

AU - Sakai, Kokki

AU - Shoyama, Yoshihiro

AU - Sato, Hiroaki

AU - Ueno, Tetsuya

PY - 2000/1/1

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Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea

Abstract

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