Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea

Kuniyoshi Shimizu; Ryuichiro Kondo; Kokki Sakai; Yoshihiro Shoyama; Hiroaki Sato; Tetsuya Ueno

doi:10.1271/bbb.64.875

Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea

Kuniyoshi Shimizu, Ryuichiro Kondo, Kokki Sakai, Yoshihiro Shoyama, Hiroaki Sato, Tetsuya Ueno

Sustainable Bioresources Science

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.

Original language	English
Pages (from-to)	875-877
Number of pages	3
Journal	Bioscience, Biotechnology and Biochemistry
Volume	64
Issue number	4
DOIs	https://doi.org/10.1271/bbb.64.875
Publication status	Published - Jan 1 2000

All Science Journal Classification (ASJC) codes

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

Access to Document

10.1271/bbb.64.875

Fingerprint Dive into the research topics of 'Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea'. Together they form a unique fingerprint.

Cite this

@article{fb29239a472f4a95bbc0c22b318d5632,

title = "Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea",

abstract = "The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.",

author = "Kuniyoshi Shimizu and Ryuichiro Kondo and Kokki Sakai and Yoshihiro Shoyama and Hiroaki Sato and Tetsuya Ueno",

year = "2000",

month = jan,

day = "1",

doi = "10.1271/bbb.64.875",

language = "English",

volume = "64",

pages = "875--877",

journal = "Bioscience, Biotechnology and Biochemistry",

issn = "0916-8451",

publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",

number = "4",

}

TY - JOUR

T1 - Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea

AU - Shimizu, Kuniyoshi

AU - Kondo, Ryuichiro

AU - Sakai, Kokki

AU - Shoyama, Yoshihiro

AU - Sato, Hiroaki

AU - Ueno, Tetsuya

PY - 2000/1/1

Y1 - 2000/1/1

N2 - The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.

AB - The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.

UR - http://www.scopus.com/inward/record.url?scp=0034171346&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034171346&partnerID=8YFLogxK

U2 - 10.1271/bbb.64.875

DO - 10.1271/bbb.64.875

M3 - Article

C2 - 10830511

AN - SCOPUS:0034171346

VL - 64

SP - 875

EP - 877

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

SN - 0916-8451

IS - 4

ER -