Steroidal saponins from Asparagus acutifolius

Marc Sautour, Tomofumi Miyamoto, Marie Aleth Lacaille-Dubois

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Six new steroidal saponins (1-6) were isolated from the roots of A. acutifolius L., together with a known spirostanol glycoside (7). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR, FABMS and HRESIMS). Compounds 4-7 demonstrated antifungal activity against the human pathogenic yeasts C. albicans, C. glabrata and C. tropicalis with MICs values between 12.5 and 100 μg/ml.

Original languageEnglish
Pages (from-to)2554-2562
Number of pages9
JournalPhytochemistry
Volume68
Issue number20
DOIs
Publication statusPublished - Oct 1 2007

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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