TY - JOUR
T1 - Steroidal saponins from the roots of Smilax aspera subsp. mauritanica
AU - Belhouchet, Zineddine
AU - Sautour, Marc
AU - Miyamoto, Tomofumi
AU - Lacaille-Dubois, Marie Aleth
PY - 2008/9/1
Y1 - 2008/9/1
N2 - Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG. (Liliaceae), together with the known curillin G (3), asparagoside E (4), asparoside A (5), asparoside B (6) and the phenolic compound resveratrol (7). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 3 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (minimum inhibitory concentrations of 25, 25 and 50 μg/ml, respectively) whereas the other compounds were inactive.
AB - Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG. (Liliaceae), together with the known curillin G (3), asparagoside E (4), asparoside A (5), asparoside B (6) and the phenolic compound resveratrol (7). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 3 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (minimum inhibitory concentrations of 25, 25 and 50 μg/ml, respectively) whereas the other compounds were inactive.
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U2 - 10.1248/cpb.56.1324
DO - 10.1248/cpb.56.1324
M3 - Article
C2 - 18758111
AN - SCOPUS:51349085094
SN - 0009-2363
VL - 56
SP - 1324
EP - 1327
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 9
ER -