Stimulus time dependence of cerebral blood flow response to photic stimulation

Y. Kuwabara, Y. Ichiya, M. Otsuka, M. Sasaki, Y. Akashi, T. Yoshida, T. Fukumura, K. Masuda, A. Ichimiya

Research output: Contribution to journalArticle

Abstract

The time dependency of rCBF response to photic stimulation in the primary visual cortices was studied using H215O bolus-injection and PET. The subjects consisted of 5 normal volunteers aged from 25 to 40 years old. Their regional CBF was measured at 2 min and 7 min after the start of photic stimulation (frequency, 10 Hz). The percentage increases of rCBF were 19.6±7.9% (mean ± SD, range: 8.9-27.6%) in the primary visual cortex on the left side and 23.2±13.6% (2.5-35.8%) on the right side at 2 min, respectively, while, in comparison, they were 25.3±20.0% (1.8-49.7%) on the left side and 25.3±16.4% (3.5-44.5%) on the right side at 7 min, respectively. No significant difference was found in the rCBF responses between at 2 min and 7 min. Therefore, the taming effect does not need to be considered when carrying out a photic stimulation study.

Original languageEnglish
Pages (from-to)1491-1495
Number of pages5
JournalKakuigaku
Volume30
Issue number12
Publication statusPublished - Dec 1 1993

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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    Kuwabara, Y., Ichiya, Y., Otsuka, M., Sasaki, M., Akashi, Y., Yoshida, T., Fukumura, T., Masuda, K., & Ichimiya, A. (1993). Stimulus time dependence of cerebral blood flow response to photic stimulation. Kakuigaku, 30(12), 1491-1495.