Structural characterization and protein adsorption property of hydroxyapatite particles modified with zinc ions

Satoshi Hayakawa, Kanae Ando, Kanji Tsuru, Akiyoshi Osaka, Eiji Fujii, Koji Kawabata, Christian Bonhomme, Florence Babonneau

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

Zinc-containing hydroxyapatite particles (Zn/HAp) were prepared by an ion exchange reaction process involving hydroxyapatite (HAp) particles with aqueous solutions containing various amounts of zinc nitrate. The Zn2+ ion was partially substituted for the Ca2+ ion position in the HAp lattice, and hence, the obtained samples had changed little in crystallinity, particle size, and specific surface area. Adsorption of bovine serum albumin (BSA) and β2-microglobulin (β2-MG) in solutions containing both BSA and β2-MG was examined. As the Zn 2+ ion content in the apatites increased, the adsorbed amount of BSA was almost constant, whereas that of β2-MG increased.

Original languageEnglish
Pages (from-to)565-569
Number of pages5
JournalJournal of the American Ceramic Society
Volume90
Issue number2
DOIs
Publication statusPublished - Feb 1 2007

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Materials Chemistry

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