Among other homologues, amphidinol 3 (AM3) is the most potent antifungal compound isolated from the dinoflagellate Amphidinium klebsii. AM3 undergoes conformational changes in organic solvents while it takes relatively fixed configuration in a membrane model. By using NMR data of peracetyl AM3, we were able to confirm the configuration of C50-C51 of AM3 which remained uncertain in our previous study.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Organic Chemistry