Structure determination of juvenile hormone from chagas disease vectors, rhodnius prolixus and triatoma infestans

Keiji Matsumoto, Yoko Yasuno, Kohei Yasuda, Tsuyoshi Hayashi, Shin G. Goto, Tetsuro Shinada

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

The juvenile hormone (JH) is a key hormone of insects. In this study, the first structure determination of JH of Rhodnius prolixus (Heteroptera; Reduviidae) known historically as the insect for which the juvenile hormone was discovered, is reported. This species is also known as a medically important pest associated with Chagas disease. The relative and absolute stereochemistry was unambiguously determined to be methyl (2R,3S)-3-((E)-6-((R)-3,3-dimethyloxiran-2-yl)-4-methylhex-3-en-1-yl)-3-methyloxirane-2-carboxylate (JHSB3) by highly sensitive UPLC MS/MS method.

Original languageEnglish
Pages (from-to)538-541
Number of pages4
JournalChemistry Letters
Volume49
Issue number5
DOIs
Publication statusPublished - May 2020
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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