TY - JOUR
T1 - Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum
AU - Lacaille-Dubois, Marie Aleth
AU - Timité, Gaoussou
AU - Mitaine-Offer, Anne Claire
AU - Miyamoto, Tomofumi
AU - Ramezani, Mohammad
AU - Rustaiyan, Abdolhossein
AU - Mirjolet, Jean Francois
AU - Duchamp, Olivier
PY - 2010/5/1
Y1 - 2010/5/1
N2 - From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).
AB - From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).
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U2 - 10.1002/mrc.2577
DO - 10.1002/mrc.2577
M3 - Article
C2 - 20209583
AN - SCOPUS:77951855387
VL - 48
SP - 370
EP - 374
JO - Magnetic Resonance in Chemistry
JF - Magnetic Resonance in Chemistry
SN - 0749-1581
IS - 5
ER -
