From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).
All Science Journal Classification (ASJC) codes
- Materials Science(all)