Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

Marie Aleth Lacaille-Dubois; Gaoussou Timité; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Mohammad Ramezani; Abdolhossein Rustaiyan; Jean Francois Mirjolet; Olivier Duchamp

doi:10.1002/mrc.2577

Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

Marie Aleth Lacaille-Dubois, Gaoussou Timité, Anne Claire Mitaine-Offer, Tomofumi Miyamoto, Mohammad Ramezani, Abdolhossein Rustaiyan, Jean Francois Mirjolet, Olivier Duchamp

Pharmaceutical Health Care and Sciences

Research output: Contribution to journal › Article

10 Citations (Scopus)

Abstract

From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).

Original language	English
Pages (from-to)	370-374
Number of pages	5
Journal	Magnetic Resonance in Chemistry
Volume	48
Issue number	5
DOIs	https://doi.org/10.1002/mrc.2577
Publication status	Published - May 1 2010

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All Science Journal Classification (ASJC) codes

Chemistry(all)
Materials Science(all)

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Lacaille-Dubois, M. A., Timité, G., Mitaine-Offer, A. C., Miyamoto, T., Ramezani, M., Rustaiyan, A., ... Duchamp, O. (2010). Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum. Magnetic Resonance in Chemistry, 48(5), 370-374. https://doi.org/10.1002/mrc.2577

Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum. / Lacaille-Dubois, Marie Aleth; Timité, Gaoussou; Mitaine-Offer, Anne Claire; Miyamoto, Tomofumi; Ramezani, Mohammad; Rustaiyan, Abdolhossein; Mirjolet, Jean Francois; Duchamp, Olivier.

In: Magnetic Resonance in Chemistry, Vol. 48, No. 5, 01.05.2010, p. 370-374.

Research output: Contribution to journal › Article

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