Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

Marie Aleth Lacaille-Dubois; Gaoussou Timité; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Mohammad Ramezani; Abdolhossein Rustaiyan; Jean Francois Mirjolet; Olivier Duchamp

doi:10.1002/mrc.2577

Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

Marie Aleth Lacaille-Dubois, Gaoussou Timité, Anne Claire Mitaine-Offer, Tomofumi Miyamoto, Mohammad Ramezani, Abdolhossein Rustaiyan, Jean Francois Mirjolet, Olivier Duchamp

Pharmaceutical Health Care and Sciences

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).

Original language	English
Pages (from-to)	370-374
Number of pages	5
Journal	Magnetic Resonance in Chemistry
Volume	48
Issue number	5
DOIs	https://doi.org/10.1002/mrc.2577
Publication status	Published - May 1 2010

All Science Journal Classification (ASJC) codes

Chemistry(all)
Materials Science(all)

Access to Document

10.1002/mrc.2577

Fingerprint Dive into the research topics of 'Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum'. Together they form a unique fingerprint.

Cite this

Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum. / Lacaille-Dubois, Marie Aleth; Timité, Gaoussou; Mitaine-Offer, Anne Claire; Miyamoto, Tomofumi; Ramezani, Mohammad; Rustaiyan, Abdolhossein; Mirjolet, Jean Francois; Duchamp, Olivier.

In: Magnetic Resonance in Chemistry, Vol. 48, No. 5, 01.05.2010, p. 370-374.

Research output: Contribution to journal › Article › peer-review

@article{c97611a6ffec402089790f9dddf11bfd,

title = "Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum",

abstract = "From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).",

author = "Lacaille-Dubois, {Marie Aleth} and Gaoussou Timit{\'e} and Mitaine-Offer, {Anne Claire} and Tomofumi Miyamoto and Mohammad Ramezani and Abdolhossein Rustaiyan and Mirjolet, {Jean Francois} and Olivier Duchamp",

year = "2010",

month = may,

day = "1",

doi = "10.1002/mrc.2577",

language = "English",

volume = "48",

pages = "370--374",

journal = "Magnetic Resonance in Chemistry",

issn = "0749-1581",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

AU - Lacaille-Dubois, Marie Aleth

AU - Timité, Gaoussou

AU - Mitaine-Offer, Anne Claire

AU - Miyamoto, Tomofumi

AU - Ramezani, Mohammad

AU - Rustaiyan, Abdolhossein

AU - Mirjolet, Jean Francois

AU - Duchamp, Olivier

PY - 2010/5/1

Y1 - 2010/5/1

N2 - From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).

AB - From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1f rom A. sordidum and A. lilacinum, 2f romA. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50.The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-0-β-D- galactopyranosylgypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D- glucopyranosyl-(1--6)]-β-D-galactopyranoside (1) and gypsogenic acid-28-0-β-D-glucopyranosyl-(1--3)-β-D-glucopyranosyl-(1- 6)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116).

UR - http://www.scopus.com/inward/record.url?scp=77951855387&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951855387&partnerID=8YFLogxK

U2 - 10.1002/mrc.2577

DO - 10.1002/mrc.2577

M3 - Article

C2 - 20209583

AN - SCOPUS:77951855387

VL - 48

SP - 370

EP - 374

JO - Magnetic Resonance in Chemistry

JF - Magnetic Resonance in Chemistry

SN - 0749-1581

IS - 5

ER -