Structured triacylglycerol containing medium-chain fatty acids in sn-1(3) facilitates the absorption of dietary long-chain fatty acids in rats

Octavio Carvajal, Masanobu Sakono, Hirofumi Sonori, Masahiro Nakayama, Taiji Kishi, Masao Sato, Ikuo Ikeda, Michihiro Sugano, Katsumi Imaizumi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A study was carried out to examine if the positional distribution of medium chain fatty acids (MCF) in triacylglycerol influences dietary fat absorption in rats. Two types of structure-specific fats, one predominantly composed of MCF in sn-1(3) and linoleic acid in sn-2 [sn-1(3)MCF-structured] and the others of MCF in sn-2 and linoleic acid in sn-1(3) [sn-2MCF-structured], were initially prepared, and the two structure-specific fats were interesterified and designated as sn-1(3)MCF-interesterified and sn-2MCF-interesterified. Synthetic fat was mixed with an equal amount of cocoa butter (103 g/kg of diet) and was supplemented to the AIN93G-based diet. Rats were fed on the diets for 4 wk. Long-chain saturated fatty acids were the predominant fatty acids excreted into the feces, and the positional distribution of MCF resulted in an altered fat absorption rate (%) of 81.8, 82.5, 84.2 and 86.3 for the rats fed on the diets containing sn-2MCF-structured, sn-1(3)MCF-interesterified, sn-2MCF-interesterified and sn-1(3)MCF-structured fats, respectively. The proportion of MCF in the serum, liver and adipose tissue triacylglycerols was not affected by the MCF distribution of the dietary fats. These results indicate that the distribution of MCF in dietary triacylglycerol is a determinant of intestinal fat absorption.

Original languageEnglish
Pages (from-to)793-798
Number of pages6
JournalBioscience, Biotechnology and Biochemistry
Volume64
Issue number4
DOIs
Publication statusPublished - Jan 1 2000

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Rats
Triglycerides
Fatty Acids
Fats
Nutrition
Diet
Dietary Fats
Linoleic Acid
Intestinal Absorption
Feces
Liver
Adipose Tissue
Tissue

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Structured triacylglycerol containing medium-chain fatty acids in sn-1(3) facilitates the absorption of dietary long-chain fatty acids in rats. / Carvajal, Octavio; Sakono, Masanobu; Sonori, Hirofumi; Nakayama, Masahiro; Kishi, Taiji; Sato, Masao; Ikeda, Ikuo; Sugano, Michihiro; Imaizumi, Katsumi.

In: Bioscience, Biotechnology and Biochemistry, Vol. 64, No. 4, 01.01.2000, p. 793-798.

Research output: Contribution to journalArticle

Carvajal, Octavio ; Sakono, Masanobu ; Sonori, Hirofumi ; Nakayama, Masahiro ; Kishi, Taiji ; Sato, Masao ; Ikeda, Ikuo ; Sugano, Michihiro ; Imaizumi, Katsumi. / Structured triacylglycerol containing medium-chain fatty acids in sn-1(3) facilitates the absorption of dietary long-chain fatty acids in rats. In: Bioscience, Biotechnology and Biochemistry. 2000 ; Vol. 64, No. 4. pp. 793-798.
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