Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.

Mariko Aso; John Walter Mirc; Manami Kurita; Noboru Koga; Hiroshi Suemune

doi:10.1093/nass/nrm082

Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.

Mariko Aso, John Walter Mirc, Manami Kurita, Noboru Koga, Hiroshi Suemune

Chemo-Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

2-N-tert-Butylaminoxylpurines (1) and (2) were synthesized from 2'-deoxy-6-chloropurine derivative by lithiation strategy. Effects of motion of 1 and 2 on EPR spectra were studied by EPR measurement in sucrose solution at various temperatures. The single stranded and duplexed 15-mers containing 1 showed the clear difference in the EPR spectra to indicate 1 has the potential to accurately study the dynamics of purine residues.

Original language	English
Pages (from-to)	163-164
Number of pages	2
Journal	Nucleic acids symposium series (2004)
Issue number	51
DOIs	https://doi.org/10.1093/nass/nrm082
Publication status	Published - 2007

All Science Journal Classification (ASJC) codes

Medicine(all)

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title = "Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.",

abstract = "2-N-tert-Butylaminoxylpurines (1) and (2) were synthesized from 2'-deoxy-6-chloropurine derivative by lithiation strategy. Effects of motion of 1 and 2 on EPR spectra were studied by EPR measurement in sucrose solution at various temperatures. The single stranded and duplexed 15-mers containing 1 showed the clear difference in the EPR spectra to indicate 1 has the potential to accurately study the dynamics of purine residues.",

author = "Mariko Aso and Mirc, {John Walter} and Manami Kurita and Noboru Koga and Hiroshi Suemune",

year = "2007",

doi = "10.1093/nass/nrm082",

language = "English",

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journal = "Nucleic acids symposium series (2004)",

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AU - Aso, Mariko

AU - Mirc, John Walter

AU - Kurita, Manami

AU - Koga, Noboru

AU - Suemune, Hiroshi

PY - 2007

Y1 - 2007

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AB - 2-N-tert-Butylaminoxylpurines (1) and (2) were synthesized from 2'-deoxy-6-chloropurine derivative by lithiation strategy. Effects of motion of 1 and 2 on EPR spectra were studied by EPR measurement in sucrose solution at various temperatures. The single stranded and duplexed 15-mers containing 1 showed the clear difference in the EPR spectra to indicate 1 has the potential to accurately study the dynamics of purine residues.

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JO - Nucleic acids symposium series (2004)

JF - Nucleic acids symposium series (2004)

IS - 51

ER -

Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.

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