Abstract
This study demonstrated the vasorelaxation effect of small peptides and their underlying mechanisms as a novel function of blood pressure-lowering peptides. In particular, the small peptide Trp-His elicits not only a vasorelaxation effect in isolated aorta but also an anti-atherosclerotic effect in vivo. Viewing the composition off ood products as a mixture of many components, the synergistic effect on vasorelaxation by the combination of multifood compounds was also investigated. In this review article, we summarize the aforementioned beneficial effects of food compounds on vascular functions as well as the intestinal absorption and bioavailability of these bioactive peptides, clarified by using LC-MS and/or MALDI-MS imaging analyses.
| Original language | English |
|---|---|
| Pages (from-to) | 285-293 |
| Number of pages | 9 |
| Journal | Nippon Shokuhin Kagaku Kogaku Kaishi |
| Volume | 64 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jan 1 2017 |
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All Science Journal Classification (ASJC) codes
- Food Science
Cite this
Study on the physiological benefits of food compounds on vascular health and their underlying mechanisms. / Tanaka, Mitsuru.
In: Nippon Shokuhin Kagaku Kogaku Kaishi, Vol. 64, No. 6, 01.01.2017, p. 285-293.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Study on the physiological benefits of food compounds on vascular health and their underlying mechanisms
AU - Tanaka, Mitsuru
PY - 2017/1/1
Y1 - 2017/1/1
N2 - This study demonstrated the vasorelaxation effect of small peptides and their underlying mechanisms as a novel function of blood pressure-lowering peptides. In particular, the small peptide Trp-His elicits not only a vasorelaxation effect in isolated aorta but also an anti-atherosclerotic effect in vivo. Viewing the composition off ood products as a mixture of many components, the synergistic effect on vasorelaxation by the combination of multifood compounds was also investigated. In this review article, we summarize the aforementioned beneficial effects of food compounds on vascular functions as well as the intestinal absorption and bioavailability of these bioactive peptides, clarified by using LC-MS and/or MALDI-MS imaging analyses.
AB - This study demonstrated the vasorelaxation effect of small peptides and their underlying mechanisms as a novel function of blood pressure-lowering peptides. In particular, the small peptide Trp-His elicits not only a vasorelaxation effect in isolated aorta but also an anti-atherosclerotic effect in vivo. Viewing the composition off ood products as a mixture of many components, the synergistic effect on vasorelaxation by the combination of multifood compounds was also investigated. In this review article, we summarize the aforementioned beneficial effects of food compounds on vascular functions as well as the intestinal absorption and bioavailability of these bioactive peptides, clarified by using LC-MS and/or MALDI-MS imaging analyses.
UR - http://www.scopus.com/inward/record.url?scp=85021746330&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021746330&partnerID=8YFLogxK
U2 - 10.3136/nskkk.64.285
DO - 10.3136/nskkk.64.285
M3 - Review article
AN - SCOPUS:85021746330
VL - 64
SP - 285
EP - 293
JO - Nippon Shokuhin Kagaku Kogaku Kaishi
JF - Nippon Shokuhin Kagaku Kogaku Kaishi
SN - 1341-027X
IS - 6
ER -