Study on the physiological benefits of food compounds on vascular health and their underlying mechanisms

Research output: Contribution to journalReview article

Abstract

This study demonstrated the vasorelaxation effect of small peptides and their underlying mechanisms as a novel function of blood pressure-lowering peptides. In particular, the small peptide Trp-His elicits not only a vasorelaxation effect in isolated aorta but also an anti-atherosclerotic effect in vivo. Viewing the composition off ood products as a mixture of many components, the synergistic effect on vasorelaxation by the combination of multifood compounds was also investigated. In this review article, we summarize the aforementioned beneficial effects of food compounds on vascular functions as well as the intestinal absorption and bioavailability of these bioactive peptides, clarified by using LC-MS and/or MALDI-MS imaging analyses.

Original languageEnglish
Pages (from-to)285-293
Number of pages9
JournalNippon Shokuhin Kagaku Kogaku Kaishi
Volume64
Issue number6
DOIs
Publication statusPublished - Jan 1 2017

Fingerprint

blood vessels
Blood Vessels
vasodilation
Vasodilation
peptides
Food
Peptides
Health
tryptophyl-histidine
intestinal absorption
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Intestinal Absorption
aorta
Biological Availability
blood pressure
Aorta
bioavailability
image analysis
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Food Science

Cite this

Study on the physiological benefits of food compounds on vascular health and their underlying mechanisms. / Tanaka, Mitsuru.

In: Nippon Shokuhin Kagaku Kogaku Kaishi, Vol. 64, No. 6, 01.01.2017, p. 285-293.

Research output: Contribution to journalReview article

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