Subendocardial small infarct in the superior ventricular septum as a cause of sudden death

Naoki Nishida, Noriaki Ikeda, Yosei Katayama, Keiko Kudo, Tomoya Takasaki

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In autopsy files from April 1999 to April 2001, five cases showed macroscopic subendocardial small infarct above 1cm diameter in the superior ventricular septum (SVS) near the atrioventricular (AV) junction, and all five were finally considered to be sudden cardiac death after full investigation. All these small infarcts in these Japanese patients were located at the posterior site of the SVS, an area mainly nourished by branches which ramified from the AV node artery and which branched from the right coronary artery (RCA). Four of the five showed acute (A) or subacute (SA) foci in or around the healed (H) lesion and surviving myocytes were visible in infarcts, in all cases, which suggested a recurrent or chronic prolonged ischemia in the territory. Four of the five had a significant stenosis of the RCA and in the other one, there was an anomalous origin of the RCA. As all five had also small artery disease in the SVS, small infarct of the posterior SVS may have formed by hemodynamic impairment in the territory of the AV node artery caused by RCA disorders. We consider the evidence of macroscopic small infarct of the posterior SVS greatly aids in determining the cause of sudden death in forensic autopsy and may be notable lesion for discussing the pathogenesis of sudden cardiac death with RCA disorder.

Original languageEnglish
Pages (from-to)62-67
Number of pages6
JournalForensic Science International
Volume138
Issue number1-3
DOIs
Publication statusPublished - Dec 17 2003

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Ventricular Septum
Sudden Death
Cause of Death
Coronary Vessels
Atrioventricular Node
Arteries
Sudden Cardiac Death
Autopsy
Coronary Stenosis
Muscle Cells
Ischemia
Hemodynamics

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Subendocardial small infarct in the superior ventricular septum as a cause of sudden death. / Nishida, Naoki; Ikeda, Noriaki; Katayama, Yosei; Kudo, Keiko; Takasaki, Tomoya.

In: Forensic Science International, Vol. 138, No. 1-3, 17.12.2003, p. 62-67.

Research output: Contribution to journalArticle

Nishida, Naoki ; Ikeda, Noriaki ; Katayama, Yosei ; Kudo, Keiko ; Takasaki, Tomoya. / Subendocardial small infarct in the superior ventricular septum as a cause of sudden death. In: Forensic Science International. 2003 ; Vol. 138, No. 1-3. pp. 62-67.
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