Successful treatment of invasive zygomycosis based on a prompt diagnosis using molecular methods in a patient with acute myelogenous leukemia

Junichiro Yuda; Koji Kato; Yoshikane Kikushige; Kiyofumi Ohkusu; Makiko Kiyosuke; Keiji Sakamoto; Seido Oku; Noriko Miyake; Masako Kadowaki; Tadafumi Iino; Kazuki Tanimoto; Katsuto Takenaka; Hiromi Iwasaki; Toshihiro Miyamoto; Nobuyuki Shimono; Takanori Teshima; Koichi Akashi

doi:10.2169/internalmedicine.53.1366

Successful treatment of invasive zygomycosis based on a prompt diagnosis using molecular methods in a patient with acute myelogenous leukemia

Junichiro Yuda, Koji Kato, Yoshikane Kikushige, Kiyofumi Ohkusu, Makiko Kiyosuke, Keiji Sakamoto, Seido Oku, Noriko Miyake, Masako Kadowaki, Tadafumi Iino, Kazuki Tanimoto, Katsuto Takenaka, Hiromi Iwasaki, Toshihiro Miyamoto, Nobuyuki Shimono, Takanori Teshima, Koichi Akashi

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6 Citations (Scopus)

Abstract

Zygomycosis is a lethal and invasive mold infection that is often associated with hematological malignancies. The keys for successful treatment include making a rapid diagnosis and appropriately administering an-tifungal agents. We herein report the early diagnosis of a case of zygomycosis in a patient with acute myeloid leukemia using a deoxyribonucleic acid sequence analysis. We successfully performed allogeneic he-matopoietic stem cell transplantation with the use of high-dose liposomal amphotericin B and granulocyte transfusion.

Original language	English
Pages (from-to)	1087-1091
Number of pages	5
Journal	Internal Medicine
Volume	53
Issue number	10
DOIs	https://doi.org/10.2169/internalmedicine.53.1366
Publication status	Published - 2014

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.53.1366

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Yuda, J., Kato, K., Kikushige, Y., Ohkusu, K., Kiyosuke, M., Sakamoto, K., Oku, S., Miyake, N., Kadowaki, M., Iino, T., Tanimoto, K., Takenaka, K., Iwasaki, H., Miyamoto, T., Shimono, N., Teshima, T., & Akashi, K. (2014). Successful treatment of invasive zygomycosis based on a prompt diagnosis using molecular methods in a patient with acute myelogenous leukemia. Internal Medicine, 53(10), 1087-1091. https://doi.org/10.2169/internalmedicine.53.1366

Yuda, J, Kato, K , Kikushige, Y, Ohkusu, K, Kiyosuke, M, Sakamoto, K, Oku, S, Miyake, N, Kadowaki, M, Iino, T, Tanimoto, K, Takenaka, K, Iwasaki, H, Miyamoto, T, Shimono, N, Teshima, T & Akashi, K 2014, 'Successful treatment of invasive zygomycosis based on a prompt diagnosis using molecular methods in a patient with acute myelogenous leukemia', Internal Medicine, vol. 53, no. 10, pp. 1087-1091. https://doi.org/10.2169/internalmedicine.53.1366

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abstract = "Zygomycosis is a lethal and invasive mold infection that is often associated with hematological malignancies. The keys for successful treatment include making a rapid diagnosis and appropriately administering an-tifungal agents. We herein report the early diagnosis of a case of zygomycosis in a patient with acute myeloid leukemia using a deoxyribonucleic acid sequence analysis. We successfully performed allogeneic he-matopoietic stem cell transplantation with the use of high-dose liposomal amphotericin B and granulocyte transfusion.",

author = "Junichiro Yuda and Koji Kato and Yoshikane Kikushige and Kiyofumi Ohkusu and Makiko Kiyosuke and Keiji Sakamoto and Seido Oku and Noriko Miyake and Masako Kadowaki and Tadafumi Iino and Kazuki Tanimoto and Katsuto Takenaka and Hiromi Iwasaki and Toshihiro Miyamoto and Nobuyuki Shimono and Takanori Teshima and Koichi Akashi",

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doi = "10.2169/internalmedicine.53.1366",

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AU - Yuda, Junichiro

AU - Kato, Koji

AU - Kikushige, Yoshikane

AU - Ohkusu, Kiyofumi

AU - Kiyosuke, Makiko

AU - Sakamoto, Keiji

AU - Oku, Seido

AU - Miyake, Noriko

AU - Kadowaki, Masako

AU - Iino, Tadafumi

AU - Tanimoto, Kazuki

AU - Takenaka, Katsuto

AU - Iwasaki, Hiromi

AU - Miyamoto, Toshihiro

AU - Shimono, Nobuyuki

AU - Teshima, Takanori

AU - Akashi, Koichi

PY - 2014

Y1 - 2014

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AB - Zygomycosis is a lethal and invasive mold infection that is often associated with hematological malignancies. The keys for successful treatment include making a rapid diagnosis and appropriately administering an-tifungal agents. We herein report the early diagnosis of a case of zygomycosis in a patient with acute myeloid leukemia using a deoxyribonucleic acid sequence analysis. We successfully performed allogeneic he-matopoietic stem cell transplantation with the use of high-dose liposomal amphotericin B and granulocyte transfusion.

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Successful treatment of invasive zygomycosis based on a prompt diagnosis using molecular methods in a patient with acute myelogenous leukemia

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