Successful treatment of myelodysplastic syndrome (MDS)-related intestinal Behçet's disease by up-front cord blood transplantation

Atsushi Nonami, Katsuto Takenaka, Chinatsu Sumida, Kumiko Aizawa, Kenjiro Kamezaki, Toshihiro Miyamoto, Naoki Harada, Koji Nagafuji, Takanori Teshima, Mine Harada

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

Behçet's disease is a chronic, relapsing, inflammatory disease of unknown origin. The association of myelodysplastic syndrome and Behçet's disease is rare, and recent reports have indicated that immunosuppressive agents alone are not sufficient to control Behçet's disease associated with MDS and many patients die of infection or hemorrhage. We report a case of MDS with intestinal Behçet's disease. We performed cord blood transplantation with a myeloablative regimen as the primary treatment. The patient achieved complete remission for both diseases, which continued for more than 16 months. Our experience suggests that CBT may provide a potent therapeutic option for the treatment of MDS-related Behçet's disease.

Original languageEnglish
Pages (from-to)1753-1756
Number of pages4
JournalInternal Medicine
Volume46
Issue number20
DOIs
Publication statusPublished - Oct 15 2007

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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