Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome

Motoaki Shiratsuchi; Yosuke Kitamura; Youko Suehiro; Susumu Taniguchi; Yoshiyuki Sakai; Takashi Sugimura; Takayoshi Fukutomi; Yasuji Yoshikawa; Satoshi Shiokawa; Shoichiro Ikuyama; Junji Nishimura

doi:10.1007/s10165-003-0242-9

Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome

Motoaki Shiratsuchi, Yosuke Kitamura, Youko Suehiro, Susumu Taniguchi, Yoshiyuki Sakai, Takashi Sugimura, Takayoshi Fukutomi, Yasuji Yoshikawa, Satoshi Shiokawa, Shoichiro Ikuyama, Junji Nishimura

Department of Endocrine and Metabolic Diseases / Diabetes Mellitus

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A 68-year-old woman was admitted to our hospital with xerophthalmia, xerostomia, leukopenia, and thrombocytopenia. She was diagnosed to have Sjögren's syndrome and autoimmune cytopenia. After 11 months, she was readmitted with severe anemia and reticulocytopenia. Mild hemolysis was seen, and bone marrow aspirate showed markedly decreased erythropoiesis. An association of pure red cell aplasia (PRCA) and autoimmune hemolytic anemia was diagnosed. After treatment with cyclosporine and prednisolone, her anemia dramatically improved. We discuss the mechanism of PRCA associated with Sjögren's syndrome.

Original language	English
Pages (from-to)	363-366
Number of pages	4
Journal	Modern Rheumatology
Volume	13
Issue number	4
DOIs	https://doi.org/10.1007/s10165-003-0242-9
Publication status	Published - 2003

All Science Journal Classification (ASJC) codes

Rheumatology

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10.1007/s10165-003-0242-9

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Shiratsuchi, M., Kitamura, Y., Suehiro, Y., Taniguchi, S., Sakai, Y., Sugimura, T., Fukutomi, T., Yoshikawa, Y., Shiokawa, S., Ikuyama, S., & Nishimura, J. (2003). Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome. Modern Rheumatology, 13(4), 363-366. https://doi.org/10.1007/s10165-003-0242-9

Shiratsuchi, M, Kitamura, Y, Suehiro, Y, Taniguchi, S, Sakai, Y, Sugimura, T, Fukutomi, T, Yoshikawa, Y, Shiokawa, S, Ikuyama, S & Nishimura, J 2003, 'Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome', Modern Rheumatology, vol. 13, no. 4, pp. 363-366. https://doi.org/10.1007/s10165-003-0242-9

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title = "Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sj{\"o}gren's syndrome",

abstract = "A 68-year-old woman was admitted to our hospital with xerophthalmia, xerostomia, leukopenia, and thrombocytopenia. She was diagnosed to have Sj{\"o}gren's syndrome and autoimmune cytopenia. After 11 months, she was readmitted with severe anemia and reticulocytopenia. Mild hemolysis was seen, and bone marrow aspirate showed markedly decreased erythropoiesis. An association of pure red cell aplasia (PRCA) and autoimmune hemolytic anemia was diagnosed. After treatment with cyclosporine and prednisolone, her anemia dramatically improved. We discuss the mechanism of PRCA associated with Sj{\"o}gren's syndrome.",

author = "Motoaki Shiratsuchi and Yosuke Kitamura and Youko Suehiro and Susumu Taniguchi and Yoshiyuki Sakai and Takashi Sugimura and Takayoshi Fukutomi and Yasuji Yoshikawa and Satoshi Shiokawa and Shoichiro Ikuyama and Junji Nishimura",

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AU - Shiratsuchi, Motoaki

AU - Kitamura, Yosuke

AU - Suehiro, Youko

AU - Taniguchi, Susumu

AU - Sakai, Yoshiyuki

AU - Sugimura, Takashi

AU - Fukutomi, Takayoshi

AU - Yoshikawa, Yasuji

AU - Shiokawa, Satoshi

AU - Ikuyama, Shoichiro

AU - Nishimura, Junji

PY - 2003

Y1 - 2003

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AB - A 68-year-old woman was admitted to our hospital with xerophthalmia, xerostomia, leukopenia, and thrombocytopenia. She was diagnosed to have Sjögren's syndrome and autoimmune cytopenia. After 11 months, she was readmitted with severe anemia and reticulocytopenia. Mild hemolysis was seen, and bone marrow aspirate showed markedly decreased erythropoiesis. An association of pure red cell aplasia (PRCA) and autoimmune hemolytic anemia was diagnosed. After treatment with cyclosporine and prednisolone, her anemia dramatically improved. We discuss the mechanism of PRCA associated with Sjögren's syndrome.

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Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome

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