Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome

Motoaki Shiratsuchi, Yosuke Kitamura, Youko Suehiro, Susumu Taniguchi, Yoshiyuki Sakai, Takashi Sugimura, Takayoshi Fukutomi, Yasuji Yoshikawa, Satoshi Shiokawa, Shoichiro Ikuyama, Junji Nishimura

Research output: Contribution to journalArticle

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Abstract

A 68-year-old woman was admitted to our hospital with xerophthalmia, xerostomia, leukopenia, and thrombocytopenia. She was diagnosed to have Sjögren's syndrome and autoimmune cytopenia. After 11 months, she was readmitted with severe anemia and reticulocytopenia. Mild hemolysis was seen, and bone marrow aspirate showed markedly decreased erythropoiesis. An association of pure red cell aplasia (PRCA) and autoimmune hemolytic anemia was diagnosed. After treatment with cyclosporine and prednisolone, her anemia dramatically improved. We discuss the mechanism of PRCA associated with Sjögren's syndrome.

Original languageEnglish
Pages (from-to)363-366
Number of pages4
JournalModern Rheumatology
Volume13
Issue number4
DOIs
Publication statusPublished - Dec 1 2003

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Pure Red-Cell Aplasia
Prednisolone
Cyclosporine
Anemia
Xerophthalmia
Autoimmune Hemolytic Anemia
Xerostomia
Erythropoiesis
Leukopenia
Hemolysis
Thrombocytopenia
Bone Marrow
Therapeutics

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome. / Shiratsuchi, Motoaki; Kitamura, Yosuke; Suehiro, Youko; Taniguchi, Susumu; Sakai, Yoshiyuki; Sugimura, Takashi; Fukutomi, Takayoshi; Yoshikawa, Yasuji; Shiokawa, Satoshi; Ikuyama, Shoichiro; Nishimura, Junji.

In: Modern Rheumatology, Vol. 13, No. 4, 01.12.2003, p. 363-366.

Research output: Contribution to journalArticle

Shiratsuchi, M, Kitamura, Y, Suehiro, Y, Taniguchi, S, Sakai, Y, Sugimura, T, Fukutomi, T, Yoshikawa, Y, Shiokawa, S, Ikuyama, S & Nishimura, J 2003, 'Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome', Modern Rheumatology, vol. 13, no. 4, pp. 363-366. https://doi.org/10.1007/s10165-003-0242-9
Shiratsuchi, Motoaki ; Kitamura, Yosuke ; Suehiro, Youko ; Taniguchi, Susumu ; Sakai, Yoshiyuki ; Sugimura, Takashi ; Fukutomi, Takayoshi ; Yoshikawa, Yasuji ; Shiokawa, Satoshi ; Ikuyama, Shoichiro ; Nishimura, Junji. / Successful treatment of pure red cell aplasia and autoimmune cytopenia with cyclosporine and prednisolone in a patient with Sjögren's syndrome. In: Modern Rheumatology. 2003 ; Vol. 13, No. 4. pp. 363-366.
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