Successful treatment of refractory systemic lupus erythematosus with intravenous immunoglobulins

K. Akashi, K. Nagasawa, T. Mayumi, E. Yokota, N. Oochi, T. Kusaba

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Abstract

Two cases of refractory systemic lupus erythematosus (SLE) were successfully treated with intravenous immunoglobulins (IVIg). In Case 1, the immediate recovery from severe pancytopenia and the improvement of proteinuria were observed, following IVIg therapy in high doses (450 mg/kg) for 5 consecutive days. In Case 2, 3 courses of IVIg therapy (100 mg/kg) for 6 to 8 days resulted in a significant reduction of massive proteinuria. In both cases, the improvement of immunological variables was also seen.

Original languageEnglish
Pages (from-to)375-379
Number of pages5
JournalJournal of Rheumatology
Volume17
Issue number3
Publication statusPublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Akashi, K., Nagasawa, K., Mayumi, T., Yokota, E., Oochi, N., & Kusaba, T. (1990). Successful treatment of refractory systemic lupus erythematosus with intravenous immunoglobulins. Journal of Rheumatology, 17(3), 375-379.