Sugar sensing utilizing aggregation properties of a boronic-acid-appended porphyrin

Hiroto Murakami, Takeshi Nagasaki, Itaru Hamachi, Seiji Shinkai

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

It was shown that monosaccharides can be sensitively detected utilizing aggregation properties of a boronic-acid-appended porphyrin. Since the magnitude of the spectral change is correlated with the association tendency between sugars and boronic acids, the origin of the spectral change is related to the increase in the hydrophilicity in the sugar-binding site.

Original languageEnglish
Pages (from-to)6273-6276
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number39
DOIs
Publication statusPublished - Sep 24 1993

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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