Sugar sensing utilizing aggregation properties of a boronic-acid-appended porphyrin

Hiroto Murakami, Takeshi Nagasaki, Itaru Hamachi, Seiji Shinkai

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

It was shown that monosaccharides can be sensitively detected utilizing aggregation properties of a boronic-acid-appended porphyrin. Since the magnitude of the spectral change is correlated with the association tendency between sugars and boronic acids, the origin of the spectral change is related to the increase in the hydrophilicity in the sugar-binding site.

Original languageEnglish
Pages (from-to)6273-6276
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number39
DOIs
Publication statusPublished - Sep 24 1993

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Boronic Acids
Porphyrins
Sugars
Agglomeration
Sugar Acids
Monosaccharides
Hydrophilicity
Hydrophobic and Hydrophilic Interactions
Binding Sites

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Sugar sensing utilizing aggregation properties of a boronic-acid-appended porphyrin. / Murakami, Hiroto; Nagasaki, Takeshi; Hamachi, Itaru; Shinkai, Seiji.

In: Tetrahedron Letters, Vol. 34, No. 39, 24.09.1993, p. 6273-6276.

Research output: Contribution to journalArticle

Murakami, Hiroto ; Nagasaki, Takeshi ; Hamachi, Itaru ; Shinkai, Seiji. / Sugar sensing utilizing aggregation properties of a boronic-acid-appended porphyrin. In: Tetrahedron Letters. 1993 ; Vol. 34, No. 39. pp. 6273-6276.
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