Sugars intensify the inhibitory effect of phenylboronic acid on the hydrolytic activity of α-chymotrypsin

Hikaru Suenaga, Kazuaki Nakashima, Seiji Shinkai

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The inhibitory effect of phenylboronic acid which acts as a transition state analogue for certain peptidases is efficiently intensified by added saccharides: this finding enables us to control the enzyme activity with sugars.

Original languageEnglish
Pages (from-to)29-30
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number1
DOIs
Publication statusPublished - 1995
Externally publishedYes

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Chymotrypsin
Enzyme activity
Sugars
Peptide Hydrolases
Acids
Enzymes
benzeneboronic acid

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

Cite this

Sugars intensify the inhibitory effect of phenylboronic acid on the hydrolytic activity of α-chymotrypsin. / Suenaga, Hikaru; Nakashima, Kazuaki; Shinkai, Seiji.

In: Journal of the Chemical Society, Chemical Communications, No. 1, 1995, p. 29-30.

Research output: Contribution to journalArticle

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