Suppression of sexual behavior in male Japanese medaka (Oryzias latipes) exposed to 17β-estradiol

Yuji Oshima, Ik Joon Kang, Makito Kobayashi, Kei Nakayama, Nobuyoshi Imada, Tsuneo Honjo

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Mating pairs of Japanese medaka (Oryzias latipes) received 17β-estradiol (E2; dose, 3 and 30 μg/g body weight daily) in their diet and E2-free diet (control) for two weeks. The effect on reproductive success was assessed in the mating pairs, and sexual and nonsexual behaviors in the male were quantified. The fecundities of the E2-treated groups were reduced significantly (p < 0.05) compared with those of control, and the sexual behaviors (following, dancing, floating, and crossing) of male fish in response to prostaglandin F2α (PG)-injected E2-unexposed females were suppressed dramatically. While the fertility of spawned eggs and the frequencies of the nonsexual behaviors of resting and swimming in a straight line performed by male were unchanged in E2-exposed groups. Therefore, sexual behavior in male may be linked with reproductive success in mating pair of madaka exposed to E2. This assay for sexual behavior using PG may provide a useful tool for assessing the effect of endocrine-disrupting chemicals.

Original languageEnglish
Pages (from-to)429-436
Number of pages8
JournalChemosphere
Volume50
Issue number3
DOIs
Publication statusPublished - Jan 1 2003

Fingerprint

Oryzias
sexual behavior
Dinoprost
Nutrition
Sexual Behavior
Estradiol
Endocrine Disruptors
Fish
reproductive success
Fertility
Assays
diet
Diet
Eggs
fecundity
fertility
Fishes
Body Weight
assay
egg

All Science Journal Classification (ASJC) codes

  • Environmental Engineering
  • Environmental Chemistry
  • Chemistry(all)
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

Suppression of sexual behavior in male Japanese medaka (Oryzias latipes) exposed to 17β-estradiol. / Oshima, Yuji; Kang, Ik Joon; Kobayashi, Makito; Nakayama, Kei; Imada, Nobuyoshi; Honjo, Tsuneo.

In: Chemosphere, Vol. 50, No. 3, 01.01.2003, p. 429-436.

Research output: Contribution to journalArticle

Oshima, Yuji ; Kang, Ik Joon ; Kobayashi, Makito ; Nakayama, Kei ; Imada, Nobuyoshi ; Honjo, Tsuneo. / Suppression of sexual behavior in male Japanese medaka (Oryzias latipes) exposed to 17β-estradiol. In: Chemosphere. 2003 ; Vol. 50, No. 3. pp. 429-436.
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