Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

Hiroki Obayashi; Rie Wakabayashi; Noriho Kamiya; Masahiro Goto

doi:10.1039/d2cc05910j

Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

Hiroki Obayashi, Rie Wakabayashi, Noriho Kamiya, Masahiro Goto

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Abstract

This study investigated the localization of artificial peptide supramolecular fibers in liquid-liquid phase separation (LLPS). Hierarchical organization led to the localization of supramolecules in LLPS droplets. Moreover, proteins were recruited into confined droplets by the physical adsorption of proteins on the supramolecules, enabling an enhanced cascade reaction.

Original language	English
Pages (from-to)	414-417
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	4
DOIs	https://doi.org/10.1039/d2cc05910j
Publication status	Published - Dec 5 2022

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/d2cc05910j

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abstract = "This study investigated the localization of artificial peptide supramolecular fibers in liquid-liquid phase separation (LLPS). Hierarchical organization led to the localization of supramolecules in LLPS droplets. Moreover, proteins were recruited into confined droplets by the physical adsorption of proteins on the supramolecules, enabling an enhanced cascade reaction.",

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AU - Kamiya, Noriho

AU - Goto, Masahiro

PY - 2022/12/5

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Supramolecular localization in liquid-liquid phase separation and protein recruitment in confined droplets

Abstract

All Science Journal Classification (ASJC) codes

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