Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

Shunsuke Sugimoto, Rui Moriyama, Takeshi Mori, Yasuhiko Iwasaki

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)

    Abstract

    In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.

    Original languageEnglish
    Pages (from-to)17428-17430
    Number of pages3
    JournalChemical Communications
    Volume51
    Issue number98
    DOIs
    Publication statusPublished - Jan 1 2015

    All Science Journal Classification (ASJC) codes

    • Catalysis
    • Electronic, Optical and Magnetic Materials
    • Ceramics and Composites
    • Chemistry(all)
    • Surfaces, Coatings and Films
    • Metals and Alloys
    • Materials Chemistry

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