Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells

Shunsuke Sugimoto, Rui Moriyama, Takeshi Mori, Yasuhiko Iwasaki

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.

Original languageEnglish
Pages (from-to)17428-17430
Number of pages3
JournalChemical Communications
Volume51
Issue number98
DOIs
Publication statusPublished - Jan 1 2015

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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